Evidence map›Paper›PMID 31728202›Full record

ArticleNPJ biofilms and microbiomes

Single microcolony diffusion analysis in

Jagadish Sankaran, Nicholas J H J Tan, Ka Pui But, Yehuda Cohen, Scott A Rice, Thorsten Wohland

Open access · goldAbstract read
In one paragraph

Article in NPJ biofilms and microbiomes. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.

  1. Molecular imaging of bacterial biofilms-a systematic review.Critical reviews in microbiology · 2024
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Case Study: Illuminating the Nanoscale World of Microbiology.Methods in molecular biology (Clifton, N.J.) · 2026
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Antibiotics (Basel, Switzerland) · 2024
    Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Jagadish Sankaran1Department of Biological Sciences, National University of Singapore, 117558 Singapore, Singapore.
Nicholas J H J Tan3Singapore Centre for Environmental Life Sciences Engineering, Nanyang Technological University, 637551 Singapore, Singapore.
Ka Pui But2Centre for BioImaging Sciences, National University of Singapore, 117557 Singapore, Singapore.
Yehuda Cohen3Singapore Centre for Environmental Life Sciences Engineering, Nanyang Technological University, 637551 Singapore, Singapore.
Scott A Rice3Singapore Centre for Environmental Life Sciences Engineering, Nanyang Technological University, 637551 Singapore, Singapore.ORCID 0000-0002-9486-2343
Thorsten Wohland1Department of Biological Sciences, National University of Singapore, 117558 Singapore, Singapore.ORCID 0000-0002-0148-4321
National University of Singapore · SGNanyang Technological University · SGUniversity of Technology Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The influence of the biofilm matrix on molecular diffusion is commonly hypothesized to be responsible for emergent characteristics of biofilms such as nutrient trapping, signal accumulation and antibiotic tolerance. Hence quantifying the molecular diffusion coefficient is important to determine whether there is an influence of biofilm microenvironment on the mobility of molecules. Here, we use single plane illumination microscopy fluorescence correlation spectroscopy (SPIM-FCS) to obtain 3D diffusion coefficient maps with micrometre spatial and millisecond temporal resolution of entire

Indexed as

DiffusionAnti-Bacterial AgentsBiofilmsDextransExtracellular Polymeric Substance MatrixImaging, Three-DimensionalPseudomonas aeruginosaSpatio-Temporal AnalysisSpectrometry, FluorescenceTobramycinAnti-Bacterial AgentsDextransTobramycinAntimicrobialsBacteriologyBiofilms

Identifiers

PMID31728202
PMCPMC6841743
OpenAlexW2984596163

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.