Evidence map›Paper›PMID 31728052›Full record

ArticleLeukemia2020

The impact of anti-thymocyte globulin on the outcomes of Patients with AML with or without measurable residual disease at the time of allogeneic hematopoietic cell transplantation.

Arnon Nagler, Bhagirathbhai Dholaria, Myriam Labopin, Gerard Socie, Anne Huynh, Maija Itälä-Remes, Eric Deconinck, Ibrahim Yakoub-Agha, Jean-Yves Cahn, Jean-Henri Bourhis and 5 more

Abstract read
PubMed Publisher
In one paragraph

Article in Leukemia, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

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  3. MRD-directed and risk-adapted individualized stratified treatment of AML.Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 7 institutions in 4 countries.

Arnon Nagler *Hematology Department, Chaim Sheba Medical Center, Tel Hashomer, Israel.
Bhagirathbhai Dholaria *Department of Hematology-Oncology, Vanderbilt University Medical Center, Nashville, TN, USA. Bhagirathbhai.R.Dholaria@vumc.org.ORCID http://orcid.org/0000-0003-2371-3655
Myriam Labopin *Service d'Hématologie Clinique et Thérapie Cellulaire, Hôpital Saint-Antoine, AP-HP, Sorobonne University, and INSERM UMRs 938, Paris, France.
Gerard SocieBone Marrow Transplantation Department, CHU Saint-Louis, Paris, France.ORCID http://orcid.org/0000-0002-2114-7533
Anne HuynhOncopole, Institut Universitaire du Cancer Toulouse, Toulouse, France.
Maija Itälä-RemesStem Cell Transplantation Unit, HUCH Comprehensive Cancer Center, Helsinki, Finland.
Eric DeconinckService d'Hématologie, CHU Besançon, Besançon, France.ORCID http://orcid.org/0000-0002-6006-8088
Ibrahim Yakoub-AghaCHU de Lille, LIRIC, INSERM U995, Université de Lille, Lille, France.
Jean-Yves CahnService d'Hématologie, CHU Grenoble Alpes-Université Grenoble Alpes, Grenoble, France.
Jean-Henri BourhisDivision of Hematology, Department of Medical Oncology, Gustave Roussy, institut de cancérologie, BMT Service, Villejuif, France.
Hélène Labussière-WalletService Hématologie, Centre Hospitalier Lyon Sud, Hospices Civils de Lyon, Pierre Bénite, Lyon, France.
Sylvain ChantepieInstitut d'hématologie de Basse-Normandie, CHU CAEN, Caen, France.
Jordi EsteveHematology department, Hospital Clínic de Barcelona, Barcelona, Spain.
Bipin SavaniDepartment of Hematology-Oncology, Vanderbilt University Medical Center, Nashville, TN, USA.ORCID http://orcid.org/0000-0002-3304-9965
Mohamad MohtyService d'Hématologie Clinique et Thérapie Cellulaire, Hôpital Saint-Antoine, AP-HP, Sorobonne University, and INSERM UMRs 938, Paris, France.
Inserm · FRVanderbilt University Medical Center · USCentre Hospitalier Universitaire de Grenoble · FRHospices Civils de Lyon · FRHospital Clínic de Barcelona · ESInstitut Gustave Roussy · FRInstitut universitaire du cancer de Toulouse Oncopole · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Measurable residual disease (MRD) status pre-allogeneic hematopoietic cell transplantation (allo-HCT) has been shown to predict transplant outcomes. We investigated the effect of Anti-Thymocyte Globulin (ATG) on acute myelogenous leukemia (AML) relapse by pretransplant MRD status. AML patients undergoing allo-HCT in first complete remission from either a matched sibling or unrelated donor during the 2006-2017 period were selected. Outcomes of 1509 patients (MRD

Indexed as

AdolescentAdultAgedAntilymphocyte SerumFemaleFollow-Up StudiesGraft vs Host DiseaseHematopoietic Stem Cell TransplantationHumansImmunosuppressive AgentsLeukemia, Myeloid, AcuteMaleMiddle AgedNeoplasm, ResidualPrognosisRetrospective StudiesAntilymphocyte SerumImmunosuppressive Agents

Identifiers

PMID31728052
OpenAlexW2987986628

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.