ArticleEuropean journal of clinical nutrition2020
Association between atherogenic index of plasma and subclinical renal damage over a 12-year follow-up: Hanzhong adolescent hypertension study.
Article in European journal of clinical nutrition, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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10 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.
- Atherogenic index of plasma and risk of diabetic nephropathy in type 2 diabetes: A meta‑analysis.Biomolecules & biomedicine · 2025Pooled it
- Association of atherogenic index of plasma with urine albumin-to-creatinine ratio in Chinese urban adults: a cross-sectional study.Renal failure · 2026Article
- A study of perirenal and epicardial fat thickness, oxidative stress, inflammation, and metabolic risk in pre-dialysis diabetic and non-diabetic CKD patients.International urology and nephrology · 2026Article
- The relationship between the atherogenic index of plasma and postoperative myocardial injury following non-cardiac surgery under general anaesthesia: a retrospective cohort study.BMC cardiovascular disorders · 2025Article
- Atherogenic indices and risk of chronic kidney disease in metabolic derangements: Gangnam Severance Medical Cohort.Kidney research and clinical practice · 2025Article
- Association of Atherogenic Index of Plasma with Cardiometabolic Risk Factors and Markers in Lean 14-to-20-Year-Old Individuals: A Cross-Sectional Study.Children (Basel, Switzerland) · 2023Article
- A mathematical model for thrombotic risk assessment in type 2 diabetes.Bioinformation · 2023Article
- Association between the atherogenic index of plasma and major adverse cardiovascular events among non-diabetic hypertensive older adults.Lipids in health and disease · 2022Article
- Elevated atherogenic index and higher triglyceride increase risk of kidney function decline: a 7-year cohort study in Chinese adults.Renal failure · 2021Article
- Blood pressure and long-term subclinical cardiovascular outcomes in low-risk young adults: Insights from Hanzhong adolescent hypertension cohort.Journal of clinical hypertension (Greenwich, Conn.) · 2021Article
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10 authors at 1 institution in 1 country.
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Abstract
backgroundA high atherogenic index of plasma (AIP) is associated with increased cardiovascular risk and higher serum uric acid levels, but whether AIP is a strong risk factor for developing subclinical renal damage (SRD) is unknown. This study aimed to explore the effect of AIP variations on the prevalence of SRD in a 12-year follow-up study.
methods(1) The cross-sectional study enrolled 2485 participants from the Hanzhong cohort in 2017; (2) A total of 202 participants were included in the small longitudinal cohort from 2005 to 2017. Longitudinal analysis was used to determine whether an elevated AIP predicts the development of SRD.
resultsIn the cross-sectional analysis, the AIP level was correlated with the estimated glomerular filtration rate (eGFR) and urinary albumin-to-creatine ratio (uACR) (P < 0.05). The age-adjusted odds ratio (OR) for prevalent SRD in men in the high AIP group was 1.924 (1.355-2.732) (P < 0.001), while in women, the OR was 1.616 (1.049-2.490) (P = 0.030) in the high AIP group. In the longitudinal analysis, significantly higher uACR levels were found in participants with normal AIP at baseline and elevated AIP in 2013 (P < 0.05). The adjusted OR for prevalent SRD in the incident AIP group was 4.741 (1.668-13.472) (P = 0.003) compared with the control group.
conclusionsOur study indicates that elevated AIP increased the risk of developing SRD and was associated with uACR and eGFR. As a simple marker of CVD risk, AIP may emerge as a novel and reliable indicator of SRD.
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