Evidence map›Paper›PMID 31727850›Full record

ArticleJournal of the American Society of Nephrology : JASN2020

Joseph C Gigliotti, Adrienne Tin, Shirin Pourafshar, Sylvia Cechova, Yves T Wang, Sun-Sang J Sung, Gabor Bodonyi-Kovacs, Janet V Cross, Guang Yang, Nhu Nguyen and 11 more

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Society of Nephrology : JASN, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 44 citations in OpenAlex.

  1. Therapeutic potential of phytochemical compounds in cardiovascular disease: a comprehensive review.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Exogenous application of glutathione enhanced growth, nutritional orchestration and physiochemical characteristics ofPhysiology and molecular biology of plants : an international journal of functional plant biology · 2023
    Article
  12. Article
  13. Article
  14. Collectrin (American journal of physiology. Renal physiology · 2023
    Article
  15. Review
  16. Mechanistic review of sulforaphane as a chemoprotective agent in bladder cancer.American journal of clinical and experimental urology · 2023
    Review
  17. Article
  18. Glutathione-Biomolecules · 2022
    Article
  19. Association of GSTM1 Deletion With Progression of CKD in Children: Findings From the Chronic Kidney Disease in Children (CKiD) Study.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2022
    Observational
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 11 institutions in 3 countries.

Joseph C GigliottiDivision of Nephrology, Department of Medicine and.
Adrienne TinDepartment of Epidemiology and.ORCID 0000-0002-4207-5866
Shirin PourafsharDivision of Nephrology, Department of Medicine and.
Sylvia CechovaDivision of Nephrology, Department of Medicine and.
Yves T WangDivision of Nephrology, Department of Medicine, University of Rochester School of Medicine, Rochester, New York.ORCID 0000-0003-2095-3506
Sun-Sang J SungDivision of Nephrology, Department of Medicine and.
Gabor Bodonyi-KovacsDivision of Nephrology, Department of Medicine and.
Janet V CrossDepartment of Pathology, University of Virginia School of Medicine, Charlottesville, Virginia.
Guang YangDivision of Nephrology, Heinrich-Heine University of Dusseldorf, Dusseldorf, Germany.
Nhu NguyenDepartment of Biomedical Sciences, Grand Valley State University, Allendale, Michigan.ORCID 0000-0003-3790-257X
Fang ChanDivision of Nephrology, Department of Medicine and.
Casey RebholzDepartment of Epidemiology and.
Bing YuDepartment of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health and.
Megan L GroveHuman Genetics Center, University of Texas Health Science Center at Houston, Houston, Texas.
Morgan E GramsWelch Center for Prevention, Epidemiology and Clinical Research, Baltimore, Maryland.
Anna KöttgenDepartment of Epidemiology and.ORCID 0000-0002-4671-3714
Robert ScharpfDepartment of Biostatistics, Johns Hopkins Bloomberg School of Public Heath, Baltimore, Maryland.
Phillip RuizDepartment of Pathology, University of Miami, Miami, Florida.
Eric BoerwinkleHuman Genetics Center, University of Texas Health Science Center at Houston, Houston, Texas.
Josef CoreshDepartment of Epidemiology and.ORCID 0000-0002-4598-0669
Thu H LeDivision of Nephrology, Department of Medicine and Thu_Le@URMC.Rochester.edu.ORCID 0000-0002-6410-1623
Welch Foundation · USJohns Hopkins University · USThe University of Texas Health Science Center at Houston · USGrand Valley State University · USHealth and Human Development (2HD) Research Network · CMHeinrich Heine University Düsseldorf · DELiberty University · USUniversity of Freiburg · DEUniversity of Miami · USUniversity of Rochester · USUniversity of Virginia · US

Funding

Kidney Disease and InflammationT32DK072922 · NIDDK · UNIVERSITY OF VIRGINIA · PI OKUSA, MARK DOUGLAS · 2006 to 2020
$2.6M
GSTM1, APOL1, and their joint contribution to severity of hypertension and chronic kidney diseaseR01DK094907 · NIDDK · UNIVERSITY OF VIRGINIA · PI LE, THU H., MYCHALECKYJ, JOSYF · 2012 to 2021
$1.7M
GST alleles and oxidant pollutants in the pathogenesis of asthmaR21HL098941 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KOLLER, BEVERLY H · 2009 to 2010
$740k
Risk of Chronic Kidney Disease Associated with GSTM1 DeletionsR21DK112087 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI TIN, ADRIENNE · 2016 to 2017
$367k
MBF Bioscience and Zeiss Microscope System for Stereology and Tissue MorphologyS10RR026799 · NCRR · UNIVERSITY OF VIRGINIA · PI OKUSA, MARK DOUGLAS · 2010 to 2010
$278k
NCRR NIH HHS S10 RR026799NHLBI NIH HHS HHSN268201100005CNHLBI NIH HHS HHSN268201100005GNHLBI NIH HHS HHSN268201100005INHLBI NIH HHS HHSN268201100006CNHLBI NIH HHS HHSN268201100007CNHLBI NIH HHS HHSN268201100007INHLBI NIH HHS HHSN268201100008CNHLBI NIH HHS HHSN268201100008INHLBI NIH HHS HHSN268201100009CNHLBI NIH HHS HHSN268201100009INHLBI NIH HHS HHSN268201100010CNHLBI NIH HHS HHSN268201100011CNHLBI NIH HHS HHSN268201100011INHLBI NIH HHS HHSN268201100012CNHLBI NIH HHS R21 HL098941NIDDK NIH HHS R01 DK094907NIDDK NIH HHS R21 DK112087NIDDK NIH HHS T32 DK072922
6 · The paper itself

Abstract

background

methodsWe generated a

results

conclusionsOur data support a role for the GSTM1 enzyme in the modulation of oxidative stress, inflammation, and protective metabolites in CKD.

Indexed as

BrassicaceaeDietGene DeletionVegetablesAnimalsDisease Models, AnimalFemaleGlutathione TransferaseHumansMaleMiceMiddle AgedRenal Insufficiency, ChronicGlutathione Transferasechronic kidney diseasegenetic renal diseaseglutathione S-transferaseinflammationkidney disease progressionoxidative stress

Identifiers

PMID31727850
PMCPMC6935006
OpenAlexW2989028043

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.