Evidence map›Paper›PMID 31727842›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2019

Imaging the dynamic recruitment of monocytes to the blood-brain barrier and specific brain regions during

Christine A Schneider, Dario X Figueroa Velez, Ricardo Azevedo, Evelyn M Hoover, Cuong J Tran, Chelsie Lo, Omid Vadpey, Sunil P Gandhi, Melissa B Lodoen

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
6.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 77 citations in OpenAlex.

  1. Characterization of an isogenicInfection and immunity · 2026
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  2. mBio · 2026
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  3. Review
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  5. Article
  6. Microbiology spectrum · 2025
    Article
  7. Article
  8. Review
  9. mBio · 2025
    Article
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  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Christine A SchneiderDepartment of Molecular Biology and Biochemistry, University of California, Irvine, CA 92697.
Dario X Figueroa VelezDepartment of Neurobiology and Behavior, University of California, Irvine, CA 92697.
Ricardo AzevedoDepartment of Neurobiology and Behavior, University of California, Irvine, CA 92697.
Evelyn M HooverDepartment of Molecular Biology and Biochemistry, University of California, Irvine, CA 92697.
Cuong J TranDepartment of Molecular Biology and Biochemistry, University of California, Irvine, CA 92697.
Chelsie LoDepartment of Neurobiology and Behavior, University of California, Irvine, CA 92697.
Omid VadpeyDepartment of Molecular Biology and Biochemistry, University of California, Irvine, CA 92697.
Sunil P GandhiDepartment of Neurobiology and Behavior, University of California, Irvine, CA 92697.ORCID 0000-0001-9493-2340
Melissa B LodoenDepartment of Molecular Biology and Biochemistry, University of California, Irvine, CA 92697; mlodoen@uci.edu.ORCID 0000-0002-3366-6840
University of California, Irvine · US

Funding

Univ.of Calif., Irvine Cancer Center Support GrantP30CA062203 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI Marian L Waterman · 1994 to 2026
$57.9M
Uncover Strategies Used By Biological SystemsP50GM076516 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI LANDER, ARTHUR D · 2007 to 2016
$25.1M
MEDICAL SCIENTIST TRAINING PROGRAMT32GM008620 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI GOLDIN, ALAN L · 1999 to 2023
$8.1M
Parasite dissemination in Toxoplasmic encephalitisR01AI120846 · NIAID · UNIVERSITY OF CALIFORNIA-IRVINE · PI LODOEN, MELISSA BRUCKNER · 2016 to 2020
$2.0M
Immunology Research Training ProgramT32AI060573 · NIAID · UNIVERSITY OF CALIFORNIA-IRVINE · PI PEARLMAN, ERIC · 2005 to 2020
$1.9M
Contributions of interhemispheric signaling to visual system processing and developmentF30EY029596 · NEI · UNIVERSITY OF CALIFORNIA-IRVINE · PI AZEVEDO, RICARDO · 2018 to 2022
$224k
Dissecting the circuits that support high acuity spatial visionF31EY028046 · NEI · UNIVERSITY OF CALIFORNIA-IRVINE · PI FIGUEROA VELEZ, DARIO XAVIER · 2017 to 2019
$119k
NCI NIH HHS P30 CA062203NEI NIH HHS F30 EY029596NEI NIH HHS F31 EY028046NIAID NIH HHS R01 AI120846NIAID NIH HHS T32 AI060573NIGMS NIH HHS P50 GM076516NIGMS NIH HHS T32 GM008620
6 · The paper itself

Abstract

Brain infection by the parasite

Indexed as

AnimalsAntigens, LyBlood-Brain BarrierBrainCX3C Chemokine Receptor 1Disease Models, AnimalFemaleMaleMiceMice, Inbred C57BLMonocytesReceptors, CCR2ToxoplasmosisAntigens, LyCcr2 protein, mouseCX3C Chemokine Receptor 1Cx3cr1 protein, mouseLy-6C antigen, mouseReceptors, CCR2blood–brain barrierCNS infectionLPSmonocyteToxoplasma gondii

Identifiers

PMID31727842
PMCPMC6900744
OpenAlexW2983439462

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.