Evidence map›Paper›PMID 31727682›Full record

ArticleGenome research2020

Copolymerization of single-cell nucleic acids into balls of acrylamide gel.

Siran Li, Jude Kendall, Sarah Park, Zihua Wang, Joan Alexander, Andrea Moffitt, Nissim Ranade, Cassidy Danyko, Bruno Gegenhuber, Stephan Fischer and 8 more

Abstract read
In one paragraph

Article in Genome research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Siran LiCold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA.
Jude KendallCold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA.
Sarah ParkCold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA.
Zihua WangCold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA.
Joan AlexanderCold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA.
Andrea MoffittCold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA.
Nissim RanadeCold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA.
Cassidy DanykoCold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA.
Bruno GegenhuberCold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA.
Stephan FischerCold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA.
Brian D RobinsonDepartment of Pathology and Laboratory Medicine, Weill Medical College of Cornell University, New York, New York 10021, USA.
Herbert LeporDepartment of Urology, New York University Langone Medical Center, New York, New York 10017, USA.
Jessica TollkuhnCold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA.
Jesse GillisCold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA.
Eric BrouzesDepartment of Biomedical Engineering, Stony Brook University, Stony Brook, New York 11794, USA.
Alex KrasnitzCold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA.
Dan LevyCold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA.
Michael WiglerCold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA.

Funding

Single-Cell Biology Shared ResourceP30CA045508 · NCI · COLD SPRING HARBOR LABORATORY · PI LINGBO ZHANG · 1987 to 2026
$118.9M
Epigenetic Regulation of Sex Differences in the BrainR01MH113628 · NIMH · COLD SPRING HARBOR LABORATORY · PI Jessica Tollkuhn · 2018 to 2026
$4.8M
CSHL Watson School of Biological SciencesT32GM065094 · NIGMS · COLD SPRING HARBOR LABORATORY · PI GANN, ALEXANDER · 2002 to 2021
$4.8M
Multiparameter single-cell genomics platform for personalized treatment of cancerR01CA181595 · NCI · STATE UNIVERSITY NEW YORK STONY BROOK · PI BROUZES, ERIC · 2014 to 2018
$2.7M
Revealing the transcriptomic basis of neuronal identity through functional meta-analysisR01MH113005 · NIMH · COLD SPRING HARBOR LABORATORY · PI GILLIS, JESSE · 2017 to 2021
$2.4M
Defining cell types, lineage, and connectivity in developing human fetal cortexU01MH105991 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI GESCHWIND, DANIEL H · 2014 to 2016
$2.0M
Heuristics to evaluate biomedical and genomic knowledge bases for validityR01LM012736 · NLM · COLD SPRING HARBOR LABORATORY · PI GILLIS, JESSE · 2017 to 2020
$1.9M
CSHL Cancer Gene Discovery and Cancer Biology Postdoctoral Research Training ProgramT32CA148056 · NCI · COLD SPRING HARBOR LABORATORY · PI TROTMAN, LLOYD C · 2011 to 2020
$1.8M
NCI NIH HHS P30 CA045508NCI NIH HHS R01 CA181595NCI NIH HHS T32 CA148056NIGMS NIH HHS T32 GM065094NIMH NIH HHS R01 MH113005NIMH NIH HHS R01 MH113628NIMH NIH HHS U01 MH105991NLM NIH HHS R01 LM012736
6 · The paper itself

Abstract

We show the use of 5'-Acrydite oligonucleotides to copolymerize single-cell DNA or RNA into balls of acrylamide

Indexed as

AcrylamideNucleic AcidsDNADNA ContaminationDNA Copy Number VariationsGene DosageGene Expression ProfilingGene LibraryHumansNeoplasmsOligonucleotide Array Sequence AnalysisPolymerizationRNASingle-Cell AnalysisAcrylamideDNANucleic AcidsRNA

Identifiers

PMID31727682
PMCPMC6961581

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.