Evidence map›Paper›PMID 31727599›Full record

ArticleEBioMedicine2019

RETRACTED: LSAMP-AS1 binds to microRNA-183-5p to suppress the progression of prostate cancer by up-regulating the tumor suppressor DCN.

Xing Hua, Zhen Liu, Min Zhou, Yan Tian, Pei-Pei Zhao, Wen-Hai Pan, Chao-Xia Li, Xiao-Xiao Huang, Ze-Xiao Liao, Qi Xian and 5 more

RetractedOpen access · goldAbstract readRetracted Publication
In one paragraph

Article in EBioMedicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 28 citations in OpenAlex.

  1. Growth suppressing effect ofCytotechnology · 2025
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  9. Noncoding RNAs in tumor metastasis: molecular and clinical perspectives.Cellular and molecular life sciences : CMLS · 2021
    Review
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  11. Review
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  13. Article
  14. lncRNAMolecular therapy. Nucleic acids · 2021
    Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 1 country.

Xing HuaDepartments of Pathology, Guangzhou Red Cross Hospital, Medical College, Jinan University, Guangzhou 510220, P.R. China.
Zhen LiuDepartment of Pathology, School of Basic Medical Sciences, Guizhou Medical University, Guiyang 550025, P.R. China.
Min ZhouDepartment of Otolaryngology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510006, P.R. China.
Yan TianDepartment of pathology, School of Basic Medical Sciences, Southern Medical University, Guanghou 510515, P.R.China; Department of pathology, Nanfang Hospital, Guanghou 510515, P.R. China; Guangdong Provincial Key Laboratory of Molecular Tumor Pathology, Guangzhou 510515, P.R. China.
Pei-Pei ZhaoDepartment of pathology, School of Basic Medical Sciences, Southern Medical University, Guanghou 510515, P.R.China; Department of pathology, Nanfang Hospital, Guanghou 510515, P.R. China; Guangdong Provincial Key Laboratory of Molecular Tumor Pathology, Guangzhou 510515, P.R. China.
Wen-Hai PanDepartments of Pathology, Guangzhou Red Cross Hospital, Medical College, Jinan University, Guangzhou 510220, P.R. China.
Chao-Xia LiDepartments of Pathology, Guangzhou Red Cross Hospital, Medical College, Jinan University, Guangzhou 510220, P.R. China.
Xiao-Xiao HuangDepartments of Pathology, Guangzhou Red Cross Hospital, Medical College, Jinan University, Guangzhou 510220, P.R. China.
Ze-Xiao LiaoDepartments of Pathology, Guangzhou Red Cross Hospital, Medical College, Jinan University, Guangzhou 510220, P.R. China.
Qi XianDepartments of Pathology, Guangzhou Red Cross Hospital, Medical College, Jinan University, Guangzhou 510220, P.R. China.
Bo ChenDepartments of Pathology, Guangzhou Red Cross Hospital, Medical College, Jinan University, Guangzhou 510220, P.R. China.
Yue HuDepartments of Pathology, Guangzhou Red Cross Hospital, Medical College, Jinan University, Guangzhou 510220, P.R. China.
Lei LengDepartments of Pathology, Guangzhou Red Cross Hospital, Medical College, Jinan University, Guangzhou 510220, P.R. China.
Xiao-Wei FangDepartments of Pathology, Guangzhou Red Cross Hospital, Medical College, Jinan University, Guangzhou 510220, P.R. China.
Li-Na YuDepartment of pathology, School of Basic Medical Sciences, Southern Medical University, Guanghou 510515, P.R.China; Department of pathology, Nanfang Hospital, Guanghou 510515, P.R. China; Guangdong Provincial Key Laboratory of Molecular Tumor Pathology, Guangzhou 510515, P.R. China. Electronic address: nana1800@smu.edu.cn.
Jinan University · CNSouthern Medical University · CNFirst Affiliated Hospital of Guangzhou University of Chinese Medicine · CNGuiyang Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal). This article has been retracted at the request of the editor after publication concerns were raised with respect to data presented in Figure 2. The journal contacted Southern Medical University, Guangzhou, Guangdong Province, China, who formed an Academic Committee to investigate. According to the “Academic Ethics and Implementation Rules” of Southern Medical University, the Committee reported evidence of improper preservation of original data and incorrect use of pictures, and recommended immediate withdrawal of the paper. Specifically, in the PC-3 group of Fig. 2H, the ‘Control’ cell migration image had been partially duplicated in the ‘Empty vector’ image. As per journal policy, original files used to create the entire figure were requested. Raw western blot images were not available for Figure 2 C+F, and experimental repeats yielded protein level discrepancies with the original published data. The editors therefore no longer have confidence in the integrity of these data.

Indexed as

Gene Expression Regulation, NeoplasticRNA InterferenceAgedAged, 80 and overCell Adhesion Molecules, NeuronalCell Line, TumorCell MovementCell ProliferationDecorinDisease ProgressionEpithelial-Mesenchymal TransitionGenes, ReporterGPI-Linked ProteinsHumansMaleMicroRNAsCell Adhesion Molecules, NeuronalDCN protein, humanDecorinGPI-Linked Proteinslimbic system-associated membrane proteinMicroRNAsMIRN185 microRNA, humanRNA, AntisenseDecorinEpithelial-mesenchymal transitionLSAMP-AS1MicroRNA-183–5pMigrationProliferationProstate cancer

Identifiers

PMID31727599
PMCPMC6921238
OpenAlexW2986303284

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.