Evidence map›Paper›PMID 31727452›Full record

ArticleJournal of cystic fibrosis : official journal of the European Cystic Fibrosis Society2020

Prevalence and factors associated with overweight and obesity in adults with cystic fibrosis: A single-center analysis.

Tasma Harindhanavudhi, Qi Wang, Jordan Dunitz, Antoinette Moran, Amir Moheet

2 registry-linked trialsAbstract read
In one paragraph

Article in Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 47 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05723445 narecruitingnot on this mapstarted 2023, after this paper: background citation

The Effects of a Low Glycemic Load Diet on Dysglycemia and Body Composition in Adults With Cystic Fibrosis-Related Diabetes

TypeinterventionalSponsorRhode Island HospitalRan2023 to 2026Enrolled15ConditionsCystic Fibrosis, Cystic Fibrosis-related Diabetes, Cystic Fibrosis With Intestinal ManifestationsArmsLow Glycemic Load Diet
NCT06837181 recruitingnot on this mapstarted 2025, after this paper: background citation

Studying the Presence of CFRD Complications With Thoughtful Recruitment (SPeCTRuM)

TypeobservationalSponsorJaeb Center for Health ResearchRan2025 to 2028Enrolled200ConditionsCystic Fibrosis (CF), Cystic Fibrosis-related Diabetes, Diabetes, RetinopathyArmsobservational study
3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Impact of Genetics on Endocrine Manifestations of Cystic Fibrosis.Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2026
    Review
  4. Prevalence of overweight and obesity in a South Texas cystic fibrosis center.Journal of clinical & translational endocrinology · 2026
    Article
  5. The endocrine complications of cystic fibrosis.Nature reviews. Endocrinology · 2026
    Review
  6. Article
  7. Article
  8. Article
  9. Observational
  10. Article
  11. Review
  12. Article
  13. Review
  14. Review
  15. 20 years of the Montreal Cystic Fibrosis Related Diabetes Screening Cohort: key insights.European respiratory review : an official journal of the European Respiratory Society · 2025
    Review
  16. Review
  17. Observational
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Tasma HarindhanavudhiDivision of Diabetes and Endocrinology, Department of Medicine, University of Minnesota, Minneapolis, United States. Electronic address: hari0049@umn.edu.
Qi WangClinical and Transitional Science Institute, University of Minnesota, Minneapolis, United States.
Jordan DunitzDivision of Pulmonary, Allergy, Critical Care, and Sleep Medicine, Department of Medicine, University of Minnesota, Minneapolis, United States.
Antoinette MoranDivision of Pediatric Endocrinology, Department of Pediatrics, University of Minnesota, Minneapolis, United States.
Amir MoheetDivision of Diabetes and Endocrinology, Department of Medicine, University of Minnesota, Minneapolis, United States.

Funding

University of Minnesota Clinical and Translational Science Institute (UMN CTSI)UL1TR002494 · NCATS · UNIVERSITY OF MINNESOTA · PI BLAZAR, BRUCE R, WEISDORF, DANIEL J · 2018 to 2022
$34.9M
NCATS NIH HHS UL1 TR002494
6 · The paper itself

Abstract

backgroundThe relation between malnutrition and pulmonary death in patients with cystic fibrosis (CF) has resulted in intensive nutritional intervention over the last few decades, leading to a significant decline in underweight and the emergence of overweight/obesity as a potential new problem.

methodsWe performed a cross-sectional database analysis of 484 adults with CF seen at the University of Minnesota CF Center between January 2015-January 2017, to determine the prevalence and pulmonary/cardiovascular risk factors associated with overweight and obesity in this population.

resultsMean age was 35.2 ± 11.6 years. 5.2% were underweight (BMI<18.5 kg/m

conclusionsOverweight/obesity is common in adults with CF including those with severe genotypes. Lung function is better in the overweight/obese and lipid levels are within the normal range, albeit higher than in normal/underweight.

Indexed as

Cystic FibrosisMalnutritionObesityOverweightThinnessAdultBody Mass IndexCholesterolCorrelation of DataFemaleHeart Disease Risk FactorsHumansMaleNutritional StatusPrevalenceRespiratory Function TestsCholesterolCystic FibrosisObesityPrevalence

Identifiers

PMID31727452
PMCPMC7680669

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.