Evidence map›Paper›PMID 31727121›Full record

ArticleCritical care (London, England)2019

Left ventricular wall findings in non-electrocardiography-gated contrast-enhanced computed tomography after extracorporeal cardiopulmonary resuscitation.

Kazuhiro Sugiyama, Masamichi Takahashi, Kazuki Miyazaki, Takuto Ishida, Mioko Kobayashi, Yuichi Hamabe

Open access · goldAbstract read
In one paragraph

Article in Critical care (London, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Kazuhiro SugiyamaTertiary Emergency Medical Center, Tokyo Metropolitan Bokutoh Hospital, 23-15 Kotobashi, 4-Chome, Sumida-ku, Tokyo, 130-8575, Japan. kazusugi0422@hotmail.com.ORCID http://orcid.org/0000-0002-9849-4381
Masamichi TakahashiThe Department of Radiology, Tokyo Metropolitan Bokutoh Hospital, 23-15 Kotobashi, 4-Chome, Sumida-ku, Tokyo, 130-8575, Japan.
Kazuki MiyazakiTertiary Emergency Medical Center, Tokyo Metropolitan Bokutoh Hospital, 23-15 Kotobashi, 4-Chome, Sumida-ku, Tokyo, 130-8575, Japan.
Takuto IshidaTertiary Emergency Medical Center, Tokyo Metropolitan Bokutoh Hospital, 23-15 Kotobashi, 4-Chome, Sumida-ku, Tokyo, 130-8575, Japan.
Mioko KobayashiTertiary Emergency Medical Center, Tokyo Metropolitan Bokutoh Hospital, 23-15 Kotobashi, 4-Chome, Sumida-ku, Tokyo, 130-8575, Japan.
Yuichi HamabeTertiary Emergency Medical Center, Tokyo Metropolitan Bokutoh Hospital, 23-15 Kotobashi, 4-Chome, Sumida-ku, Tokyo, 130-8575, Japan.
Tokyo Metropolitan Bokutoh Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFew studies have reported left ventricular wall findings in contrast-enhanced computed tomography (CE-CT) after extracorporeal cardiopulmonary resuscitation (ECPR). This study examined left ventricular wall CE-CT findings after ECPR and evaluated the association between these findings and the results of coronary angiography and prognosis.

methodsWe evaluated out-of-hospital cardiac arrest patients who were treated with ECPR and subsequently underwent both non-electrocardiography-gated CE-CT and coronary angiography at our center between January 2011 and April 2018. Left ventricular wall CE-CT findings were classified as follows: (1) homogeneously enhanced (HE; the left ventricular wall was homogeneously enhanced), (2) segmental defect (SD; the left ventricular wall was not segmentally enhanced according to the coronary artery territory), (3) total defect (TD; the entire left ventricular wall was not enhanced), and (4) others. Successful weaning from extracorporeal membrane oxygenation, survival to hospital discharge, and predictive ability of significant stenosis on coronary angiography were compared among patients with HE, SD, and TD patterns.

resultsA total of 74 patients (median age, 59 years) were eligible, 50 (68%) of whom had initial shockable rhythm. Twenty-three (31%) patients survived to hospital discharge. HE, SD, TD, and other patterns were observed in 19, 33, 11, and 11 patients, respectively. The rates of successful weaning from extracorporeal membrane oxygenation (84% vs. 39% vs. 9%, p < 0.01) and survival to hospital discharge (47% vs. 27% vs. 0%, p = 0.02) were significantly different among patients with HE, SD, and TD patterns. In post hoc analysis, patients with HE patterns had a significantly higher success rate of weaning from extracorporeal membrane oxygenation than those with SD and TD patterns. SD predicted significant stenosis with a sensitivity of 74% and specificity of 94%.

conclusionsHomogenously enhanced left ventricular wall might be a predictor of good left ventricular function recovery. In contrast, total enhancement defect in the entire left ventricular wall was associated with poor outcomes. Contrast defect matching the coronary artery territory could predict significant coronary artery stenosis with good specificity. The left ventricular wall findings in non-electrocardiography-gated CE-CT after ECPR might be useful for diagnosis and prognostic prediction.

Indexed as

AgedEchocardiographyExtracorporeal Membrane OxygenationFemaleHeart VentriclesHumansMaleMiddle AgedOut-of-Hospital Cardiac ArrestResuscitationRetrospective StudiesTime FactorsTomography, X-Ray ComputedExtracorporeal cardiopulmonary resuscitationHypoenhancementLeft ventricular wallNon-electrocardiography-gated computed tomography

Identifiers

PMID31727121
PMCPMC6854640
OpenAlexW2989422138

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.