Evidence map›Paper›PMID 31727020›Full record

ArticleBMC cancer2019

Characterizing MRI features of rectal cancers with different KRAS status.

Yanyan Xu, Qiaoyu Xu, Yanhui Ma, Jianghui Duan, Haibo Zhang, Tongxi Liu, Lu Li, Hongliang Sun, Kaining Shi, Sheng Xie and 1 more

Open access · goldAbstract read
In one paragraph

Article in BMC cancer, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. The Role of Radiomics in Rectal Cancer.Journal of gastrointestinal cancer · 2023
    Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Article
  11. Review
  12. Review
  13. Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Yanyan XuDepartment of Radiology, China-Japan Friendship Hospital, No.2 Yinghua East Street, Chaoyang District, Beijing, 100029, People's Republic of China.
Qiaoyu XuDepartment of Radiology, China-Japan Friendship Hospital, No.2 Yinghua East Street, Chaoyang District, Beijing, 100029, People's Republic of China.
Yanhui MaDepartment of Radiology, China-Japan Friendship Hospital, No.2 Yinghua East Street, Chaoyang District, Beijing, 100029, People's Republic of China.
Jianghui DuanDepartment of Radiology, China-Japan Friendship Hospital, No.2 Yinghua East Street, Chaoyang District, Beijing, 100029, People's Republic of China.
Haibo ZhangDepartment of Radiology, China-Japan Friendship Hospital, No.2 Yinghua East Street, Chaoyang District, Beijing, 100029, People's Republic of China.
Tongxi LiuDepartment of Radiology, China-Japan Friendship Hospital, No.2 Yinghua East Street, Chaoyang District, Beijing, 100029, People's Republic of China.
Lu LiDepartment of Radiology, China-Japan Friendship Hospital, No.2 Yinghua East Street, Chaoyang District, Beijing, 100029, People's Republic of China.
Hongliang SunDepartment of Radiology, China-Japan Friendship Hospital, No.2 Yinghua East Street, Chaoyang District, Beijing, 100029, People's Republic of China. stentorsun@gmail.com.ORCID http://orcid.org/0000-0001-5757-752X
Kaining ShiPhilips Healthcare, Beijing, 100001, People's Republic of China.
Sheng XieDepartment of Radiology, China-Japan Friendship Hospital, No.2 Yinghua East Street, Chaoyang District, Beijing, 100029, People's Republic of China.
Wu WangDepartment of Radiology, China-Japan Friendship Hospital, No.2 Yinghua East Street, Chaoyang District, Beijing, 100029, People's Republic of China.
China-Japan Friendship Hospital · CNPhilips (China) · CN

Funding

Beijing Municipal Science & Technology Commission Z181100001718099National health and family planning commission public service 201402019National Natural Science Foundation of China 81501469
6 · The paper itself

Abstract

backgroundTo investigate whether MRI findings, including texture analysis, can differentiate KRAS mutation status in rectal cancer.

methodsTotally, 158 patients with pathologically proved rectal cancers and preoperative pelvic MRI examinations were enrolled. Patients were stratified into two groups: KRAS wild-type group (KRAS

resultsMean values of six texture parameters (Mean, Variance, Skewness, Entropy, gray-level nonuniformity, run-length nonuniformity) were significantly higher in KRAS

conclusionThe MRI findings of rectal cancer, especially texture features, showed an encouraging value for identifying KRAS status.

Indexed as

Magnetic Resonance ImagingAdultAgedChemoradiotherapyFemaleHumansMaleMiddle AgedMutationNeoadjuvant TherapyNeoplasm StagingProto-Oncogene Proteins p21(ras)Rectal NeoplasmsRectumRetrospective StudiesROC CurveKRAS protein, humanProto-Oncogene Proteins p21(ras)KRAS mutationMagnetic resonance imagingRectal cancerTexture

Identifiers

PMID31727020
PMCPMC6857233
OpenAlexW2983096248

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.