Evidence map›Paper›PMID 31726982›Full record

SynthesisBMC gastroenterology2019

Methods for diagnosing bile acid malabsorption: a systematic review.

Ivan Lyutakov, Francesco Ursini, Plamen Penchev, Giacomo Caio, Antonio Carroccio, Umberto Volta, Roberto De Giorgio

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in BMC gastroenterology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. [Bile Acid Diarrhea].The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2024
    Review
  5. Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Ivan LyutakovClinic of Gastroenterology, University Hospital "Tsaritsa Yoanna - ISUL", Sofia, Bulgaria.
Francesco UrsiniDepartment of Medical Sciences, University of Ferrara, Ferrara, Italy.
Plamen PenchevClinic of Gastroenterology, University Hospital "Tsaritsa Yoanna - ISUL", Sofia, Bulgaria.
Giacomo CaioDepartment of Medical Sciences, University of Ferrara, Ferrara, Italy.
Antonio CarroccioDiBiMIS University of Palermo, Palermo, Italy.
Umberto VoltaDepartment of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.
Roberto De GiorgioDepartment of Medical Sciences, University of Ferrara, Ferrara, Italy. roberto.degiorgio@unife.it.
University of Ferrara · ITQueen Giovanna Hospital · BGUniversity of Bologna · ITUniversity of Palermo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBile acid malabsorption (BAM) and bile acid-related diarrhea represent an under-recognized cause of chronic diarrhea mainly because of limited guidance on appropriate diagnostic and laboratory tests. We aimed to perform a systematic review of the literature in order to identify and compare the diagnostic accuracy of different diagnostic methods for patients with BAM, despite a proven gold standard test is still lacking.

methodsA PubMed literature review and a manual search were carried out. Relevant full papers, evaluating the diagnostic accuracy of different methods for BAM, were assessed. Available data were analyzed to estimate the sensitivity and specificity of each published test.

resultsOverall, more than one test was considered in published papers on BAM. The search strategy retrieved 574 articles; of these, only 16 were full papers (with a total of 2.332 patients) included in the final review. Specifically, n = 8 studies used

conclusionsOur systematic review indicates that

Indexed as

Bile Acids and SaltsBiomarkersHumansIntestinal ReabsorptionMalabsorption SyndromesSensitivity and SpecificityTaurocholic Acid23-seleno-25-homotaurocholic acidBile Acids and SaltsBiomarkersTaurocholic AcidBile acid malabsorptionBiomarkersChronic diarrheaDiagnostic accuracy

Identifiers

PMID31726982
PMCPMC6854889
OpenAlexW2988406503

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.