Evidence map›Paper›PMID 31726874›Full record

ArticleDiabetes & vascular disease research

Thiamine transporter 2 is involved in high glucose-induced damage and altered thiamine availability in cell models of diabetic retinopathy.

Elena Beltramo, Aurora Mazzeo, Tatiana Lopatina, Marina Trento, Massimo Porta

Open access · bronzeAbstract read
In one paragraph

Article in Diabetes & vascular disease research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Genetic Variants of the Human Thiamine Transporter (International journal of molecular sciences · 2025
    Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Elena BeltramoDepartment of Medical Sciences, University of Turin, Turin, Italy.ORCID 0000-0002-7868-0988
Aurora MazzeoDepartment of Medical Sciences, University of Turin, Turin, Italy.
Tatiana LopatinaDepartment of Medical Sciences, University of Turin, Turin, Italy.
Marina TrentoDepartment of Medical Sciences, University of Turin, Turin, Italy.
Massimo PortaDepartment of Medical Sciences, University of Turin, Turin, Italy.ORCID 0000-0002-3407-6017
University of Turin · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thiamine prevents high glucose-induced damage in microvasculature, and progression of retinopathy and nephropathy in diabetic animals. Impaired thiamine availability causes renal damage in diabetic patients. Two single-nucleotide polymorphisms in

Indexed as

ApoptosisCell LineCell MovementCell ProliferationCell SurvivalCellular MicroenvironmentCoculture TechniquesDiabetic RetinopathyEndothelial CellsEpendymoglial CellsGlucoseHumansMembrane Transport ProteinsPericytesRetinal VesselsSp1 Transcription FactorGlucoseMembrane Transport ProteinsSLC19A2 protein, humanSLC19A3 protein, humanSP1 protein, humanSp1 Transcription FactorThiamineTransketolaseDiabetic retinopathyinner blood–retinal barrierthiaminethiamine transportertransketolase

Identifiers

PMID31726874
PMCPMC7510357
OpenAlexW2985697804

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.