Evidence map›Paper›PMID 31726774›Full record

ArticleToxins2019

Comparative In Vitro Assessment of a Range of Commercial Feed Additives with Multiple Mycotoxin Binding Claims.

Oluwatobi Kolawole, Julie Meneely, Brett Greer, Olivier Chevallier, David S Jones, Lisa Connolly, Christopher Elliott

Open access · goldAbstract readComparative Study
In one paragraph

Article in Toxins, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 3 pooled it
7.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 3 syntheses or guidelines pooled it, 60 citations in OpenAlex.

  1. Pooled it
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  12. The efficiency of mycotoxin binding by sorbents in theJournal of veterinary research · 2024
    Article
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  14. Article
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  16. Article
  17. Artificial gut and the applications in poultry: A review.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2022
    Review
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  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Oluwatobi KolawoleInstitute for Global Food Security, Queens University Belfast, BT9 SDL, Belfast, UK.
Julie MeneelyInstitute for Global Food Security, Queens University Belfast, BT9 SDL, Belfast, UK.
Brett GreerInstitute for Global Food Security, Queens University Belfast, BT9 SDL, Belfast, UK.
Olivier ChevallierInstitute for Global Food Security, Queens University Belfast, BT9 SDL, Belfast, UK.
David S JonesSchool of Pharmacy, Queens University Belfast, Belfast BT9 7BL, UK.
Lisa ConnollyInstitute for Global Food Security, Queens University Belfast, BT9 SDL, Belfast, UK.
Christopher ElliottInstitute for Global Food Security, Queens University Belfast, BT9 SDL, Belfast, UK.
Queen's University Belfast · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Contamination of animal feed with multiple mycotoxins is an ongoing and growing issue, as over 60% of cereal crops worldwide have been shown to be contaminated with mycotoxins. The present study was carried out to assess the efficacy of commercial feed additives sold with multi-mycotoxin binding claims. Ten feed additives were obtained and categorised into three groups based on their main composition. Their capacity to simultaneously adsorb deoxynivalenol (DON), zearalenone (ZEN), fumonisin B1 (FB1), ochratoxin A (OTA), aflatoxin B1 (AFB1) and T-2 toxin was assessed and compared using an in vitro model designed to simulate the gastrointestinal tract of a monogastric animal. Results showed that only one product (a modified yeast cell wall) effectively adsorbed more than 50% of DON, ZEN, FB1, OTA, T-2 and AFB1, in the following order: AFB1 > ZEN > T-2 > DON > OTA > FB1. The remaining products were able to moderately bind AFB1 (44-58%) but had less, or in some cases, no effect on ZEN, FB1, OTA and T-2 binding (<35%). It is important for companies producing mycotoxin binders that their products undergo rigorous trials under the conditions which best mimic the environment that they must be active in. Claims on the binding efficiency should only be made when such data has been generated.

Indexed as

Animal FeedCrops, AgriculturalFood ContaminationIn Vitro TechniquesMycotoxinsMycotoxinsanimal feedfeed safetymycotoxin bindersmycotoxins

Identifiers

PMID31726774
PMCPMC6891808
OpenAlexW2986156634

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.