Evidence map›Paper›PMID 31726739›Full record

ArticleJournal of clinical medicine2019

Clinical Factors Associated with a Shorter or Longer Course of Antibiotic Treatment in Patients with Exacerbations of Bronchiectasis: A Prospective Cohort Study.

Giulia Scioscia, Rosanel Amaro, Victoria Alcaraz-Serrano, Albert Gabarrús, Patricia Oscanoa, Laia Fernandez, Rosario Menendez, Raul Mendez, Maria Pia Foschino Barbaro, Antoni Torres

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
0.2field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. A systematic literature review of the clinical and socioeconomic burden of bronchiectasis.European respiratory review : an official journal of the European Respiratory Society · 2024
    Pooled it
  3. Article
  4. Lung microbiome: new insights into bronchiectasis' outcome.Frontiers in cellular and infection microbiology · 2024
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Giulia SciosciaMedical and Surgical Sciences Department, Institute of Respiratory Disease, University of Foggia, 71121 Foggia, Italy.ORCID 0000-0002-2667-077X
Rosanel AmaroInstitute of Respiratory Disease, Hospital Clínic of Barcelona, 08036 Barcelona, Spain.
Victoria Alcaraz-SerranoFundació Clínic per la Recerca Biomèdica (FCRB), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Biomedical Research Networking Center on Respiratory Diseases (CIBERES), Hospital Clínic of Barcelona, 08036 Barcelona, Spain.ORCID 0000-0001-6036-9545
Albert GabarrúsFundació Clínic per la Recerca Biomèdica (FCRB), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Biomedical Research Networking Center on Respiratory Diseases (CIBERES), Hospital Clínic of Barcelona, 08036 Barcelona, Spain.
Patricia OscanoaInstitute of Respiratory Disease, Hospital Clínic of Barcelona, 08036 Barcelona, Spain.
Laia FernandezFundació Clínic per la Recerca Biomèdica (FCRB), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Biomedical Research Networking Center on Respiratory Diseases (CIBERES), Hospital Clínic of Barcelona, 08036 Barcelona, Spain.ORCID 0000-0001-7528-9636
Rosario MenendezPneumology Department, La Fe University and Polytechnic Hospital, La Fe Health Research Institute, 46026 Valencia, Spain.
Raul MendezPneumology Department, La Fe University and Polytechnic Hospital, La Fe Health Research Institute, 46026 Valencia, Spain.ORCID 0000-0001-6300-9836
Maria Pia Foschino BarbaroMedical and Surgical Sciences Department, Institute of Respiratory Disease, University of Foggia, 71121 Foggia, Italy.ORCID 0000-0001-9939-2697
Antoni TorresInstitute of Respiratory Disease, Hospital Clínic of Barcelona, 08036 Barcelona, Spain.ORCID 0000-0002-8643-2167
Centro de Investigación Biomédica en Red · ESHospital Universitari i Politècnic La Fe · ESUniversity of Foggia · ITHospital Clínic de Barcelona · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBronchiectasis exacerbations are often treated with prolonged antibiotic use, even though there is limited evidence for this approach. We therefore aimed to investigate the baseline clinical and microbiological findings associated with long courses of antibiotic treatment in exacerbated bronchiectasis patients.

methodsThis was a bi-centric prospective observational study of bronchiectasis exacerbated adults. We compared groups receiving short (≤14 days) and long (15-21 days) courses of antibiotic treatment.

resultsWe enrolled 191 patients (mean age 72 (63, 79) years; 108 (56.5%) females), of whom 132 (69%) and 59 (31%) received short and long courses of antibiotics, respectively. Multivariable logistic regression of the baseline variables showed that long-term oxygen therapy (LTOT), moderate-severe exacerbations, and microbiological isolation of

conclusionsDecisions about the duration of antibiotic therapy should be guided by clinical and microbiological assessments of patients with infective exacerbations.

Indexed as

antibiotic coursebronchiectasisexacerbationsseverity

Identifiers

PMID31726739
PMCPMC6912316
OpenAlexW2985308758

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.