Evidence map›Paper›PMID 31726666›Full record

ReviewJournal of clinical medicine2019

A Systematic Review and Meta-Analysis of Within-Person Changes in Cardiac Vagal Activity across the Menstrual Cycle: Implications for Female Health and Future Studies.

Katja M Schmalenberger, Tory A Eisenlohr-Moul, Lena Würth, Ekaterina Schneider, Julian F Thayer, Beate Ditzen, Marc N Jarczok

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed, 2 pooled it
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

64 citing papers in PubMed, 2 syntheses or guidelines pooled it, 109 citations in OpenAlex.

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  17. Gendering the Menstrual Cycle in Behavioral Neuroendocrinology.American journal of human biology : the official journal of the Human Biology Council · 2026
    Review
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4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Katja M SchmalenbergerInstitute of Medical Psychology, Center for Psychosocial Medicine, University Hospital Heidelberg, 69115 Heidelberg, Germany.ORCID 0000-0002-5405-1933
Tory A Eisenlohr-MoulWomen's Mental Health Research Program, Department of Psychiatry, University of Illinois at Chicago, Chicago, IL 60612, USA.
Lena WürthInstitute of Medical Psychology, Center for Psychosocial Medicine, University Hospital Heidelberg, 69115 Heidelberg, Germany.
Ekaterina SchneiderInstitute of Medical Psychology, Center for Psychosocial Medicine, University Hospital Heidelberg, 69115 Heidelberg, Germany.ORCID 0000-0003-2099-6071
Julian F ThayerDepartment of Psychological Science, School of Social Ecology, University of California Irvine, Irvine, CA 92697-7085, USA.
Beate DitzenInstitute of Medical Psychology, Center for Psychosocial Medicine, University Hospital Heidelberg, 69115 Heidelberg, Germany.
Marc N JarczokClinic for Psychosomatic Medicine and Psychotherapy, Ulm University Medical Center, 89081 Ulm, Germany.ORCID 0000-0002-6055-385X
Heidelberg University · DEUniversität Ulm · DEUniversity of California, Irvine · USUniversity of Illinois Chicago · US

Funding

Cyclical Neuroactive Steroid Changes, Arousal, and Proximal Suicide Risk: An Experimental ApproachRF1MH120843 · NIMH · UNIVERSITY OF ILLINOIS AT CHICAGO · PI EISENLOHR-MOUL, TORY ANNE · 2019 to 2019
$3.1M
Ovarian Hormone Withdrawal and Suicide Risk: An Experimental ApproachR00MH109667 · NIMH · UNIVERSITY OF ILLINOIS AT CHICAGO · PI EISENLOHR-MOUL, TORY ANNE · 2018 to 2020
$747k
Medizinischen Fakultät Heidelberg, Universität Heidelberg Physician Scientist ProgramNIH HHS R00MH109667NIMH NIH HHS R00 MH109667NIMH NIH HHS RF1 MH120843
6 · The paper itself

Abstract

Interest in cardiac vagal activity (CVA; e.g., parasympathetically-mediated heart rate variability) as a biomarker of physical and mental health has increased exponentially in recent years. However, the understanding of sources of within-person change (i.e., intra-individual variance) in CVA is lagging behind. This systematic review and meta-analysis summarizes and quantifies current empirical evidence of within-person changes in measures of CVA across the menstrual cycle in naturally-cycling premenopausal females. We conducted an extensive literature search following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement in five databases to identify observational studies with repeated measures of CVA in at least two menstrual cycle phases. A broad meta-analysis (

Indexed as

cardiac vagal activitycardiac vagal tonefemale healthheart rate variabilitymenstrual cycleovarian hormones

Identifiers

PMID31726666
PMCPMC6912442
OpenAlexW2986641591

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.