Evidence map›Paper›PMID 31725774›Full record

ArticlePloS one2019

Imported severe malaria and risk factors for intensive care: A single-centre retrospective analysis.

Alessandra D'Abramo, Luciana Lepore, Marco Iannetta, Saba Gebremeskel Tekle, Angela Corpolongo, Laura Scorzolini, Nazario Bevilacqua, Andrea Mariano, Maria Letizia Giancola, Antonella Vulcano and 6 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2025
    Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 2 countries.

Alessandra D'AbramoNational Institute for Infectious Diseases, IRCCS, Lazzaro Spallanzani, Rome, Italy.
Luciana LeporeNational Institute for Infectious Diseases, IRCCS, Lazzaro Spallanzani, Rome, Italy.
Marco IannettaNational Institute for Infectious Diseases, IRCCS, Lazzaro Spallanzani, Rome, Italy.ORCID 0000-0002-6938-8627
Saba Gebremeskel TekleNational Institute for Infectious Diseases, IRCCS, Lazzaro Spallanzani, Rome, Italy.
Angela CorpolongoNational Institute for Infectious Diseases, IRCCS, Lazzaro Spallanzani, Rome, Italy.
Laura ScorzoliniNational Institute for Infectious Diseases, IRCCS, Lazzaro Spallanzani, Rome, Italy.
Nazario BevilacquaNational Institute for Infectious Diseases, IRCCS, Lazzaro Spallanzani, Rome, Italy.
Andrea MarianoNational Institute for Infectious Diseases, IRCCS, Lazzaro Spallanzani, Rome, Italy.
Maria Letizia GiancolaNational Institute for Infectious Diseases, IRCCS, Lazzaro Spallanzani, Rome, Italy.
Antonella VulcanoNational Institute for Infectious Diseases, IRCCS, Lazzaro Spallanzani, Rome, Italy.
Micaela MarittiNational Institute for Infectious Diseases, IRCCS, Lazzaro Spallanzani, Rome, Italy.
Alessandro AgrestaNational Institute for Infectious Diseases, IRCCS, Lazzaro Spallanzani, Rome, Italy.
Mario AntoniniNational Institute for Infectious Diseases, IRCCS, Lazzaro Spallanzani, Rome, Italy.
Umberto D'AlessandroMRC Unit The Gambia at the London School of Hygiene and Tropical Medicine, Atlantic Boulevard, Fajara, The Gambia.
Emanuele NicastriNational Institute for Infectious Diseases, IRCCS, Lazzaro Spallanzani, Rome, Italy.
Spallanzani Group for Malaria Study
Istituto Nazionale per le Malattie Infettive Lazzaro Spallanzani · ITMRC Unit the Gambia · GM

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study aims to identify the risk factors for intensive care (IC) in severe malaria patients admitted to the "Lazzaro Spallanzani" National Institute for Infectious Diseases, Rome, Italy.

methodsAll patients with confirmed severe malaria and hospitalized between 2007 and 2015 were included in the analysis and stratified into two groups: those requiring IC and those who did not. Five prognostic malaria scores were estimated; clinical severity at IC unit admission was assessed using the Sequential Organ Failure Assessment and the quick-Sequential Organ Failure Assessment scores. Univariate and multivariate analysis were performed to assess factors independently associated to IC.

resultsA total of 98 severe malaria patients were included; 10 of them required IC. There were no deaths or sequelae. Patients requiring IC had higher severity scores. At the multivariate analysis, only the number of World Health Organization criteria and the aspartate aminotransferase value were independently associated with the need of IC.

conclusionsAn early and accurate assessment of the severity score is essential for the management of severe malaria patients.

Indexed as

Critical CareAdultCommunicable Diseases, ImportedComorbidityFemaleHospitalizationHumansIntensive Care UnitsMalariaMaleMiddle AgedRetrospective StudiesRisk FactorsRomeSeverity of Illness Index

Identifiers

PMID31725774
PMCPMC6855647
OpenAlexW2986585740

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.