ArticlePLoS computational biology2019
Non-equilibrium critical dynamics of bursts in θ and δ rhythms as fundamental characteristic of sleep and wake micro-architecture.
Article in PLoS computational biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 37 citations in OpenAlex.
- Physical mechanisms of human brain functions.Quantitative biology (Beijing, China) · 2025Review
- Role of the Locus Coeruleus Arousal Promoting Neurons in Maintaining Brain Criticality across the Sleep-Wake Cycle.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Distributed and dynamical communication: a mechanism for flexible cortico-cortical interactions and its functional roles in visual attention.Communications biology · 2024Article
- A predictive propensity measure to enter REM sleep.Frontiers in neuroscience · 2024Article
- Adaptive rewiring: a general principle for neural network development.Frontiers in network physiology · 2024Review
- Beyond pulsed inhibition: Alpha oscillations modulate attenuation and amplification of neural activity in the awake resting state.Cell reports · 2023Article
- Criticality of neuronal avalanches in human sleep and their relationship with sleep macro- and micro-architecture.iScience · 2023Article
- A scoping review for building a criticality-based conceptual framework of altered states of consciousness.Frontiers in systems neuroscience · 2023Article
- Anesthesia and analgesia for experimental craniotomy in mice and rats: a systematic scoping review comparing the years 2009 and 2019.Frontiers in neuroscience · 2023Article
- Time-varying information measures: an adaptive estimation of information storage with application to brain-heart interactions.Frontiers in network physiology · 2023Article
- Beyond noise to function: reframing the global brain activity and its dynamic topography.Communications biology · 2022Review
- Ensemble of coupling forms and networks among brain rhythms as function of states and cognition.Communications biology · 2022Article
- The New Field of Network Physiology: Building the Human Physiolome.Frontiers in network physiology · 2021Article
- Spatial multi-scaled chimera states of cerebral cortex network and its inherent structure-dynamics relationship in human brain.National science review · 2021Article
- Why Brain Criticality Is Clinically Relevant: A Scoping Review.Frontiers in neural circuits · 2020Article
- Network Physiology of Cortico-Muscular Interactions.Frontiers in physiology · 2020Article
- Power-law correlations and coupling of active and quiet states underlie a class of complex systems with self-organization at criticality.EPJ web of conferences · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
Abstract
Origin and functions of intermittent transitions among sleep stages, including short awakenings and arousals, constitute a challenge to the current homeostatic framework for sleep regulation, focusing on factors modulating sleep over large time scales. Here we propose that the complex micro-architecture characterizing the sleep-wake cycle results from an underlying non-equilibrium critical dynamics, bridging collective behaviors across spatio-temporal scales. We investigate θ and δ wave dynamics in control rats and in rats with lesions of sleep-promoting neurons in the parafacial zone. We demonstrate that intermittent bursts in θ and δ rhythms exhibit a complex temporal organization, with long-range power-law correlations and a robust duality of power law (θ-bursts, active phase) and exponential-like (δ-bursts, quiescent phase) duration distributions, typical features of non-equilibrium systems self-organizing at criticality. Crucially, such temporal organization relates to anti-correlated coupling between θ- and δ-bursts, and is independent of the dominant physiologic state and lesions, a solid indication of a basic principle in sleep dynamics.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.