Evidence map›Paper›PMID 31725600›Full record

Observational studyMedicine2019

Antibiotic prescribing trends in a pediatric population in Lithuania in 2003-2012: Observational study.

Egle Karinauske, Skaiste Kasciuskeviciute, Vilma Morkuniene, Kristina Garuoliene, Edmundas Kadusevicius

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Egle KarinauskeDepartment of Clinical Pharmacology, Institute of Physiology and Pharmacology, Lithuanian University of Health Sciences.
Skaiste KasciuskeviciuteDepartment of Clinical Pharmacology, Institute of Physiology and Pharmacology, Lithuanian University of Health Sciences.
Vilma MorkunieneKaunas University of Applied Science, Kaunas.
Kristina GaruolieneMinistry of Health of the Republic of Lithuania, Vilnius, Lithuania.
Edmundas KaduseviciusDepartment of Clinical Pharmacology, Institute of Physiology and Pharmacology, Lithuanian University of Health Sciences.
Lithuanian University of Health Sciences · LTCzech Academy of Sciences, Institute of Physiology · CZKaunas kolegija Higher Education Institution · LT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of this study was to determine the trends in consumption of antibiotics and evaluate the antibiotic prescription rates in the pediatric population in Lithuania during 2003 to 2012.A cross-sectional study. Data of systemic antibiotic use in pediatric population for outpatient treatment was derived from National Health Insurance Fund database. Consumption was expressed as WHO ATC defined daily dose (DDD)/1000 children/day and as a number of prescriptions written in the general population per year. Statistical analysis was performed using the SPSS/W 20.0 software (Statistical Product and Service Solutions for Windows).Total utilization of antibiotics (expressed in DDD units) during study period increased by 8.40% (from 5.67 to 6.19 DDD/1000 children/day) and by 5.96% expressed in prescription rate (from 585.84 to 622.97 prescriptions/1000 children/year). The most popular antibiotic group was macrolides which showed the highest increase of utilization 5.9 times (from 0.27 DDD/1000 children/day in 2003 to 1.66 DDD/1000 children/day in 2012).The most common indications for antibiotic prescribing for children in 2012 were acute bronchitis (25.6%), acute tonsillitis (21.7%) and acute pharyngitis (14.6%). Amoxicillin had the highest probability to be chosen to treat acute tonsillitis (prob. [probability] = .2875) and acute pharyngitis (prob. = .5553). Clarithromycin had the highest probability to be chosen to treat acute bronchitis (prob. = .4222).Most of the diseases treated with antibiotics were viral infections. The most commonly prescribed antibiotics were broad-spectrum. The consumption of antibiotics was evenly increasing during 2003 to 2012 period, but the distribution of separate antibiotic group remained the same.

Indexed as

Population SurveillanceAmbulatory CareAnti-Bacterial AgentsChildCross-Sectional StudiesDrug UtilizationFemaleHumansLithuaniaMalePractice Patterns, Physicians'Anti-Bacterial Agents

Identifiers

PMID31725600
PMCPMC6867790
OpenAlexW2989502056

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.