Evidence map›Paper›PMID 31725358›Full record

ArticleJournal of applied physiology (Bethesda, Md. : 1985)2019

Time-dependent regulation of postprandial muscle protein synthesis rates after milk protein ingestion in young men.

Stephan van Vliet, Joseph W Beals, Andrew M Holwerda, Russell S Emmons, Joy P Goessens, Scott A Paluska, Michael De Lisio, Luc J C van Loon, Nicholas A Burd

Open access · bronzeAbstract read
In one paragraph

Article in Journal of applied physiology (Bethesda, Md. : 1985), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
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  3. No effects of high-The British journal of nutrition · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Stephan van VlietDepartment of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, Urbana, Illinois.
Joseph W BealsDivision of Nutritional Sciences, University of Illinois at Urbana-Champaign, Urbana, Illinois.
Andrew M HolwerdaNUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University, Maastricht, The Netherlands.
Russell S EmmonsDivision of Nutritional Sciences, University of Illinois at Urbana-Champaign, Urbana, Illinois.
Joy P GoessensNUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University, Maastricht, The Netherlands.
Scott A PaluskaDepartment of Family Medicine, University of Illinois at Urbana-Champaign, Urbana, Illinois.
Michael De LisioSchool of Human Kinetics and Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, Ontario, Canada.ORCID 0000-0002-6462-2955
Luc J C van LoonNUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University, Maastricht, The Netherlands.
Nicholas A BurdDepartment of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, Urbana, Illinois.ORCID 0000-0001-5581-3154
University of Illinois Urbana-Champaign · USMaastricht University · NLUniversity of Ottawa · CA

Funding

WUSTL Transdisciplinary Pre- and Postdoctoral Training Program in Obesity and Cardiovascular DiseaseT32HL130357 · NHLBI · WASHINGTON UNIVERSITY · PI WILFLEY, DENISE ELLA · 2016 to 2025
$4.3M
NHLBI NIH HHS T32 HL130357
6 · The paper itself

Abstract

The anabolic action of "fast" whey protein on the regulation of postprandial muscle protein synthesis has been established to be short-lived in healthy young adults. We assessed the time course of anabolic signaling activation and stimulation of myofibrillar protein synthesis rates (MPS) after ingestion of a food source that represents a more typical meal-induced pattern of aminoacidemia. Seven young men (age: 22 ± 1 y) underwent repeated blood and biopsy sampling during primed, continuous l-[

Indexed as

AdultAmino AcidsBlood GlucoseCaseinsDietDietary ProteinsEatingHumansLeucineMaleMilk ProteinsMuscle ProteinsMuscle, SkeletalMyofibrilsPhenylalaninePostprandial PeriodAmino AcidsBlood GlucoseCaseinsDietary ProteinsLeucineMilk ProteinsMuscle ProteinsPhenylalanineWhey Proteinsanabolic signalingleucinemammalian target of rapamycinmuscle mass regulationnutrition

Identifiers

PMID31725358
PMCPMC7054632
OpenAlexW2987602755

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.