ReviewNephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association2020
The impact of biomarkers of acute kidney injury on individual patient care.
Review in Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The efficacy of novel biomarkers for the early detection and management of acute kidney injury: A systematic review.PloS one · 2025Pooled it
- Performance of urinary C-C motif chemokine ligand 14 for the prediction of persistent acute kidney injury: a systematic review and meta-analysis.Critical care (London, England) · 2023Pooled it
- Time Course of Kidney Injury Biomarkers in Children With Septic Shock: Nested Cohort Study Within the Pragmatic Pediatric Trial of Balanced Versus Normal Saline Fluid in Sepsis Trial.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2025Trial
- Article
- Electronic Phenotype for Detection, Staging, and Subtyping of Acute Kidney Injury.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2026Article
- Proenkephalin A for assessing kidney integrity and guiding KRT liberation decisions in critically ill patients.Annals of intensive care · 2026Article
- Plasma NGAL levels in stable kidney transplant recipients and the risk of allograft loss.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2024Article
- Improving awareness of kidney function through electronic urine output monitoring: a comparative study.BMC nephrology · 2022Article
- Measurement of Serum Levels of 5 Amino Acids and Dimethylamine Using Liquid Chromatography-Tandem Mass Spectrometry in Patients without Septic Associated Acute Kidney Injury and with Septic Associated Acute Kidney Injury Requiring Continuous Renal Replacement Therapy.Medical science monitor : international medical journal of experimental and clinical research · 2022Article
- Burn-Induced Acute Kidney Injury-Two-Lane Road: From Molecular to Clinical Aspects.International journal of molecular sciences · 2022Review
- The use of diagnostic tools for pediatric AKI: applying the current evidence to the bedside.Pediatric nephrology (Berlin, Germany) · 2021Review
- Clinical phenotypes of acute kidney injury are associated with unique outcomes in critically ill septic children.Pediatric research · 2021Observational
- Acute kidney injury after lung transplantation: a narrative review.Annals of translational medicine · 2021Review
- [Focus nephrology : Intensive medical care studies from 2019/2020].Der Anaesthesist · 2021Article
- Rational selection of a biomarker panel targeting unmet clinical needs in kidney injury.Clinical proteomics · 2021Review
- Effects of repeated increasing doses of cisplatin as models of acute kidney injury and chronic kidney disease in rats.Naunyn-Schmiedeberg's archives of pharmacology · 2021Article
- Artificial Intelligence in Acute Kidney Injury: From Static to Dynamic Models.Advances in chronic kidney disease · 2021Review
- Plasma Endogenous Sulfur Dioxide: A Novel Biomarker to Predict Acute Kidney Injury in Critically Ill Patients.International journal of general medicine · 2021Article
- Erythrocyte transfusion limits the role of elevated red cell distribution width on predicting cardiac surgery associated acute kidney injury.Cardiology journal · 2021Article
- Subclinical Acute Kidney Injury Is Acute Kidney Injury and Should Not Be Ignored.American journal of respiratory and critical care medicine · 2020Article
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4 authors.
Funding
Abstract
Acute kidney injury (AKI) remains a common clinical syndrome associated with increased morbidity and mortality. In the last several years there have been several advances in the identification of patients at increased risk for AKI through the use of traditional and newer functional and damage biomarkers of AKI. This article will specifically focus on the impact of biomarkers of AKI on individual patient care, focusing predominantly on the markers with the most expansive breadth of study in patients and reported literature evidence. Several studies have demonstrated that close monitoring of widely available biomarkers such as serum creatinine and urine output is strongly associated with improved patient outcomes. An integrated approach to these biomarkers used in context with patient risk factors (identifiable using electronic health record monitoring) and with tests of renal reserve may guide implementation and targeting of care bundles to optimize patient care. Besides traditional functional markers, biochemical injury biomarkers have been increasingly utilized in clinical trials both as a measure of kidney injury as well as a trigger to initiate other treatment options (e.g. care bundles and novel therapies). As the novel measures are becoming globally available, the clinical implementation of hospital-based real-time biomarker measurements involves a multidisciplinary approach. This literature review discusses the data evidence supporting both the strengths and limitations in the clinical implementation of biomarkers based on the authors' collective clinical experiences and opinions.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.