Evidence map›Paper›PMID 31724831›Full record

SynthesisInternational wound journal2020

Antimicrobial photodynamic therapy in skin wound healing: A systematic review of animal studies.

Yan Sun, Rei Ogawa, Bi-Huan Xiao, Yu-Xin Feng, Yan Wu, Liang-Hong Chen, Xing-Hua Gao, Hong-Duo Chen

Open access · bronzeAbstract readSystematic Review
In one paragraph

Synthesis in International wound journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 2 pooled it
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 2 syntheses or guidelines pooled it, 75 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Review
  5. Article
  6. Review
  7. AirborneAdvanced healthcare materials · 2026
    Article
  8. Article
  9. Article
  10. Review
  11. Observational
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Yan SunDepartment of Dermatology, The First Hospital of China Medical University, Shenyang, China.ORCID https://orcid.org/0000-0003-1780-3363
Rei OgawaDepartment of Plastic, Reconstructive and Aesthetic Surgery, Nippon Medical School, Tokyo, Japan.ORCID https://orcid.org/0000-0003-3658-555X
Bi-Huan XiaoDepartment of Dermatology, The First Hospital of China Medical University, Shenyang, China.
Yu-Xin FengDepartment of Dermatology, The First Hospital of China Medical University, Shenyang, China.
Yan WuDepartment of Dermatology, The First Hospital of China Medical University, Shenyang, China.
Liang-Hong ChenDepartment of Emergency Medicine, Shengjing Hospital of China Medical University, Shenyang, China.
Xing-Hua GaoDepartment of Dermatology, The First Hospital of China Medical University, Shenyang, China.
Hong-Duo ChenDepartment of Dermatology, The First Hospital of China Medical University, Shenyang, China.
First Hospital of China Medical University · CNChina Medical University · CNNippon Medical School Hospital · JP

Funding

111 Project D18011National Key Research and Development Program of China 2016YFC0901504
6 · The paper itself

Abstract

Bacterial infection is a common wound complication that can significantly delay healing. Classical local therapies for infected wounds are expensive and are frequently ineffective. One alternative therapy is photodynamic therapy (PDT). We conducted a systematic review to clarify whether PDT is useful for bacteria-infected wounds in animal models. PubMed and Medline were searched for articles on PDT in infected skin wounds in animals. The language was limited to English. Nineteen articles met the inclusion criteria. The overall study methodological quality was moderate, with a low-moderate risk of bias. The animal models were mice and rats. The wounds were excisional, burn, and abrasion wounds. Wound size ranged from 6 mm in diameter to 1.5 × 1.5 cm

Indexed as

AnimalsAnti-Bacterial AgentsDisease Models, AnimalMethicillin-Resistant Staphylococcus aureusPhotochemotherapySoft Tissue InjuriesStaphylococcal InfectionsWound HealingWound InfectionAnti-Bacterial Agents

Identifiers

PMID31724831
PMCPMC7948698
OpenAlexW2987756318

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.