Evidence map›Paper›PMID 31724521›Full record

ArticleBosnian journal of basic medical sciences2020

Prognostic role of NLR, PLR, and LMR in patients with pulmonary embolism.

Nuri Köse, Tarık Yıldırım, Fatih Akın, Seda Elçim Yıldırım, İbrahim Altun

Open access · goldAbstract read
In one paragraph

Article in Bosnian journal of basic medical sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
5.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 51 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Nuri KöseDepartment of Cardiology, Private Mugla Yucelen Hospital, Mugla, Turkey.
Tarık YıldırımDepartment of Cardiology, Faculty of Medicine, Balikesir University, Balıkesir, Turkey.
Fatih AkınDepartment of Cardiology, Faculty of Medicine, Mugla Sitki Kocman University, Mugla, Turkey.
Seda Elçim YıldırımDepartment of Cardiology, Faculty of Medicine, Mugla Sitki Kocman University, Mugla, Turkey.
İbrahim AltunDepartment of Cardiology, Faculty of Medicine, Mugla Sitki Kocman University, Mugla, Turkey.
Muğla University · TRBalıkesir University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pulmonary embolism (PE) is associated with significant morbidity and mortality. New biological markers are being investigated for estimating the prognosis of PE patients. Since PE is closely associated with inflammatory status, the neutrophil-lymphocyte (NLR), platelet-lymphocyte (PLR), and lymphocyte-monocyte (LMR) ratios were suggested to be useful in predicting patient outcomes. This study aimed to evaluate the prognostic role of NLR, PLR, and LMR in PE. A total of 103 PE cases from a cardiology department were included in the study. We retrospectively evaluated demographic and clinical characteristics, treatments, laboratory and imaging findings, and outcomes of patients. The median follow-up of PE patients was 39 months, and the 5-year overall survival probability was 73.8%. Out of 103 patients, 20 were classified as high risk PE cases (19.4%). Thrombolytic treatment was administered to 23 patients (22.3%). Systolic pulmonary arterial pressure was measured during one year, showing a significant decrease from 51.7 ± 15.7 mmHg at admission to 26.6 ± 4.0 mmHg at first year assessment. Age (OR: 1.06, p < 0.001) and NLR (OR: 1.52, p < 0.0019) were significantly associated with the disease status. The independent prognostic factors in moderate-low and low risk PE groups were NLR (HR: 1.17, p = 0.033) and LMR (HR: 1.58, p = 0.046). In moderate-high and high risk PE patients, the independent prognostic factors were age (HR: 1.07, p = 0.014) and PLR (HR: 1.01, p = 0.046). NLR, PLR, and LMR were associated with the prognosis of PE patients. The clinical severity of PE should be considered when utilizing these markers to assess patient outcomes.

Indexed as

Lymphocyte CountMonocytesNeutrophilsPlatelet CountAgedFemaleHumansMaleMiddle AgedPredictive Value of TestsPrognosisPulmonary EmbolismRetrospective StudiesSurvival RateThrombolytic Therapy

Identifiers

PMID31724521
PMCPMC7202190
OpenAlexW2982756535

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.