Evidence map›Paper›PMID 31724225›Full record

ReviewAlcoholism, clinical and experimental research2020

SNARE Complex-Associated Proteins and Alcohol.

Joydip Das

Open access · greenAbstract readReview
In one paragraph

Review in Alcoholism, clinical and experimental research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Synaptic Effects Induced by Alcohol.Current topics in behavioral neurosciences · 2025
    Review
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Joydip DasDepartment of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, Texas.ORCID 0000-0003-1540-5804
University of Houston · US

Funding

Role of Munc13-1 as a presynaptic effector of ethanol actionR01AA022414 · NIAAA · UNIVERSITY OF HOUSTON · PI DAS, JOYDIP · 2015 to 2019
$1.8M
NIAAA NIH HHS R01 AA022414
6 · The paper itself

Abstract

Alcohol addiction causes major health problems throughout the world, causing numerous deaths and incurring a huge economic burden to society. To develop an intervention for alcohol addiction, it is necessary to identify molecular target(s) of alcohol and associated molecular mechanisms of alcohol action. The functions of many central and peripheral synapses are impacted by low concentrations of ethanol (EtOH). While the postsynaptic targets and mechanisms are studied extensively, there are limited studies on the presynaptic targets and mechanisms. This article is an endeavor in this direction, focusing on the effect of EtOH on the presynaptic proteins associated with the neurotransmitter release machinery. Studies on the effects of EtOH at the levels of gene, protein, and behavior are highlighted in this article.

Indexed as

AlcoholismAnimalsEthanolHumansPresynaptic TerminalsProtein Structure, SecondaryProtein Structure, TertiarySNARE ProteinsSynapsesSynaptic TransmissionEthanolSNARE ProteinsAlcoholismEtOHExocytosisNeuronNeurotransmitterPostsynapticPresynapticSNARE ComplexVolatile Anesthetics

Identifiers

PMID31724225
PMCPMC6980881
OpenAlexW2988182910

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.