Evidence map›Paper›PMID 31724124›Full record

ArticleCurrent microbiology2020

Enhancement of Purified Human Colon Cancer-Specific Parasporal Toxin from Bacillus thuringiensis-LDC-501.

Jacob Jennifer Grace, Gurusamy Ramani, Rajaiah Shenbagarathai

Abstract read
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In one paragraph

Article in Current microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jacob Jennifer GraceDBT-BIF Centre, Lady Doak College, Madurai, Tamilnadu, 625002, India.
Gurusamy RamaniPG and Research Department of Zoology: Department of Biotechnology, Lady Doak College, Madurai, Tamilnadu, 625002, India.
Rajaiah ShenbagarathaiN.Rama Varier Ayurveda Foundation, Madurai, Tamilnadu, 625004, India. shenbagarathai@rediffmail.com.
Dhathri Ayurveda (India) · IN

Funding

DST-SERB SR/SO/HS/0116/2012
6 · The paper itself

Abstract

Parasporal inclusion protein of Bacillus thuringiensis-LDC-501 (Bt-LDC-501) exhibits selective cytocidal action towards human colon cancer cells. The yield of this parasporal protein was minimum in the normal culture. In order to increase the yield of protein from Bt-LDC-501 various agro-based cost-efficient nutrient sources such as corn steep liquor (CSL), sesame oil cake extract (SOC), groundnut oil cake extract (GOC), neem oil cake extract (NOC), rice bran extract (RB), wheat bran extract (WB), red gram hull extract (RGH), green gram hull extract (GGH), black gram hull extract (BGH), Mysore gram hull extract (MGH), and maize flour waste extract (MFW) were screened. Statistical experimental designs such as Plackett-Burman design (PBD) and response surface methodology (RSM) were the tools employed for the optimization of medium. Groundnut cake extract (GOC) served as a potential carbon and nitrogen source, as it induced twofold higher production of parasporal protein. Among the optimized seven media components KH

Indexed as

Antineoplastic AgentsBacillus thuringiensisBacterial ProteinsCell Line, TumorCell SurvivalHCT116 CellsHumansPlant ExtractsAntineoplastic AgentsBacterial ProteinsPlant ExtractsAnticancer proteinBacillus thuringiensis-LDC-501Cost-effectivenessOptimizationParasporin

Identifiers

PMID31724124
OpenAlexW2987789816

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.