Evidence map›Paper›PMID 31723805›Full record

ArticleHemaSphere2019

Fibrinography: A Multiwavelength Light-Scattering Assay of Fibrin Structure.

Carhel Dassi, Landry Seyve, Xabel García, Emmanuelle Bigo, Raphaël Marlu, François Caton, Benoît Polack

Open access · goldAbstract read
In one paragraph

Article in HemaSphere, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Thrombin kinetics determines robust plasma clot architecture.Research and practice in thrombosis and haemostasis · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Carhel DassiLaboratoire TIMC-IMAG/TheREx, Université Grenoble Alpes, CNRS UMR 5525, Département d'Hématologie, Institut de Biologie et de Pathologie, Centre Hospitalier Universitaire Grenoble-Alpes, Grenoble, France.
Landry SeyveLaboratoire TIMC-IMAG/TheREx, Université Grenoble Alpes, CNRS UMR 5525, Département d'Hématologie, Institut de Biologie et de Pathologie, Centre Hospitalier Universitaire Grenoble-Alpes, Grenoble, France.
Xabel GarcíaLaboratoire Rhéologie et Procédés, Université Grenoble Alpes, CNRS UMR 5520, Grenoble, France.
Emmanuelle BigoLaboratoire TIMC-IMAG/TheREx, Université Grenoble Alpes, CNRS UMR 5525, Département d'Hématologie, Institut de Biologie et de Pathologie, Centre Hospitalier Universitaire Grenoble-Alpes, Grenoble, France.
Raphaël MarluLaboratoire TIMC-IMAG/TheREx, Université Grenoble Alpes, CNRS UMR 5525, Département d'Hématologie, Institut de Biologie et de Pathologie, Centre Hospitalier Universitaire Grenoble-Alpes, Grenoble, France.
François CatonLaboratoire Rhéologie et Procédés, Université Grenoble Alpes, CNRS UMR 5520, Grenoble, France.
Benoît PolackLaboratoire TIMC-IMAG/TheREx, Université Grenoble Alpes, CNRS UMR 5525, Département d'Hématologie, Institut de Biologie et de Pathologie, Centre Hospitalier Universitaire Grenoble-Alpes, Grenoble, France.
Centre National de la Recherche Scientifique · FRTranslational Innovation in Medicine and Complexity · FRUniversité Grenoble Alpes · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We have previously developed a fibrin structural assay dedicated to purified fibrinogen-thrombin system. Here, we extend the pertinence of this test, called Fibrinography, to tissue factor-triggered plasma coagulation. We show that Fibrinography determines quantitatively the structure of fibrin fibers in plasma with an excellent reproducibility. We compare this assay with the commonly used single wavelength turbidity method, showing that the latter is not a proper structural assay, but determines essentially the fibrinogen content in plasma. In addition, we also show, in model plasmas, that Fibrinography is able to discriminate normal and hypocoagulant plasmas, and even between hypercoagulant plasmas. Therefore, Fibrinography, by measuring the final step of the coagulation cascade, may be used to evaluate patients' plasma in hypo- or hypercoagulant diseases.

Identifiers

PMID31723805
PMCPMC6745935
OpenAlexW2911960574

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.