Evidence map›Paper›PMID 31723719›Full record

ArticleJournal of the Endocrine Society2019

Colocalization of Polycystic Ovary Syndrome Candidate Gene Products in Theca Cells Suggests Novel Signaling Pathways.

Rewa Kulkarni, Maria E Teves, Angela X Han, Jan M McAllister, Jerome F Strauss

Open access · goldAbstract read
In one paragraph

Article in Journal of the Endocrine Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Pooled it
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  6. Review
  7. Article
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  15. Review
  16. The PCOS GWAS Candidate GeneJournal of the Endocrine Society · 2022
    Article
  17. The role of androgen and its related signals in PCOS.Journal of cellular and molecular medicine · 2021
    Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Rewa KulkarniDepartment of Human and Molecular Genetics, Virginia Commonwealth University, Richmond, Virginia.
Maria E TevesDepartment of Obstetrics and Gynecology, Virginia Commonwealth University, Richmond, Virginia.ORCID 0000-0001-7035-2202
Angela X HanDepartment of Pathology, Penn State Hershey College of Medicine, Hershey, Pennsylvania.
Jan M McAllisterDepartment of Pathology, Penn State Hershey College of Medicine, Hershey, Pennsylvania.ORCID 0000-0002-6910-2801
Jerome F StraussDepartment of Obstetrics and Gynecology, Virginia Commonwealth University, Richmond, Virginia.ORCID 0000-0001-6199-0480
Virginia Commonwealth University · USPenn State Milton S. Hershey Medical Center · US

Funding

Virus Vector Shared ResourceP30CA016059 · NCI · VIRGINIA COMMONWEALTH UNIVERSITY · PI Kim Felder Rhoads · 1985 to 2026
$51.0M
VCU Neuroscience Center Core GrantP30NS047463 · NINDS · VIRGINIA COMMONWEALTH UNIVERSITY · PI POVLISHOCK, JOHN T · 2003 to 2013
$5.0M
Functional Analysis of PCOS Candidate GenesR01HD083323 · NICHD · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI MCALLISTER, JAN M, STRAUSS, JEROME F · 2016 to 2020
$2.7M
17 ALPHA HYDROXYLASE EXPRESSION IN HUMAN OVARIAN CELLSR01HD033852 · NICHD · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI MCALLISTER, JAN M · 1996 to 2010
$2.4M
Mechanism of Metformin Action in Normal and PCOS Theca CellsR01HD058300 · NICHD · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI MCALLISTER, JAN M · 2008 to 2012
$1.7M
NCI NIH HHS P30 CA016059NICHD NIH HHS R01 HD033852NICHD NIH HHS R01 HD058300NICHD NIH HHS R01 HD083323NINDS NIH HHS P30 NS047463
6 · The paper itself

Abstract

Genome-wide association studies identified loci associated with polycystic ovary syndrome (PCOS), including those near the LH receptor gene (

Indexed as

androgensDENND1ALHCGRpolycystic ovary syndromeRAB5Btheca cells

Identifiers

PMID31723719
PMCPMC6839531
OpenAlexW2942551021

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.