Evidence map›Paper›PMID 31723698›Full record

ArticleJournal of clinical tuberculosis and other mycobacterial diseases2017

The experience of scaling up a decentralized, ambulatory model of care for management of multidrug-resistant tuberculosis in two regions of Ethiopia.

Yohannes Molla, Degu Jerene, Ilili Jemal, Gebrie Nigussie, Tenagne Kebede, Yewulsew Kassie, Nebiyu Hiruy, Getachew Aschale, Dereje Habte, Zewdu Gashu and 3 more

Abstract read
In one paragraph

Article in Journal of clinical tuberculosis and other mycobacterial diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  11. What will it take to eliminate drug-resistant tuberculosis?The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yohannes MollaManagement Sciences for Health, Help Ethiopia Address the Low Performance of Tuberculosis (HEAL-TB) Project, Ethiopia.
Degu JereneManagement Sciences for Health, Help Ethiopia Address the Low Performance of Tuberculosis (HEAL-TB) Project, Ethiopia.
Ilili JemalOromia Regional Health Bureau, Addis Ababa, Ethiopia.
Gebrie NigussieAmhara Regional Health Bureau, Bahir Dar, Ethiopia.
Tenagne KebedeManagement Sciences for Health, Help Ethiopia Address the Low Performance of Tuberculosis (HEAL-TB) Project, Ethiopia.
Yewulsew KassieUnited States Agency for International Development (USAID), Addis Ababa, Ethiopia.
Nebiyu HiruyManagement Sciences for Health, Help Ethiopia Address the Low Performance of Tuberculosis (HEAL-TB) Project, Ethiopia.
Getachew AschaleManagement Sciences for Health, Help Ethiopia Address the Low Performance of Tuberculosis (HEAL-TB) Project, Ethiopia.
Dereje HabteManagement Sciences for Health, Help Ethiopia Address the Low Performance of Tuberculosis (HEAL-TB) Project, Ethiopia.
Zewdu GashuManagement Sciences for Health, Help Ethiopia Address the Low Performance of Tuberculosis (HEAL-TB) Project, Ethiopia.
Yared Kebede HaileUnited States Agency for International Development (USAID), Addis Ababa, Ethiopia.
Muluken MeleseManagement Sciences for Health, Help Ethiopia Address the Low Performance of Tuberculosis (HEAL-TB) Project, Ethiopia.
Pedro SuarezManagement Sciences for Health, Health Programs Group, Arlington, Virginia, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Strong strategies, including proven service delivery models, are needed to address the growing global threat of multidrug-resistant tuberculosis (MDR-TB) in low- and middle-income settings. The objective of this study was to assess the feasibility and effectiveness of the nationally approved ambulatory service delivery model for MDR-TB treatment in two regions of Ethiopia. We used routinely reported data to describe the process and outcomes of implementing an ambulatory model for MDR-TB services in a resource-limited setting. We compared percentage improvements in the number of MDR-TB diagnostic and treatment facilities, number of MDR-TB sputum samples processed per year, and MDR-TB cases ever enrolled in care between baseline and 2015. We also calculated interim and final treatment outcomes for patients who had completed at least 12 and 24 months of follow-up, respectively. Between 2012 and 2015, the number of MDR-TB treatment-initiating centers increased from 1 to 23. The number of sputum samples tested for MDR-TB increased 20-fold, from 662 to 14,361 per year. The backlog of patients on waiting lists was cleared. The cumulative number of MDR-TB patients put on treatment increased from 56 to 790, and the treatment success rate was 75%. Rapid expansion of the ambulatory model of MDR-TB care was feasible and achieved a high treatment success rate in two regions of Ethiopia. More effort is needed to sustain the gains and further decentralize services to the community level.

Identifiers

PMID31723698
PMCPMC6850264

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.