Evidence map›Paper›PMID 31723646›Full record

ArticleKorean journal of critical care medicine2017

The Ability of the Acute Physiology and Chronic Health Evaluation (APACHE) IV Score to Predict Mortality in a Single Tertiary Hospital.

Jae Woo Choi, Young Sun Park, Young Seok Lee, Yeon Hee Park, Chaeuk Chung, Dong Il Park, In Sun Kwon, Ju Sang Lee, Na Eun Min, Jeong Eun Park and 4 more

Abstract read
In one paragraph

Article in Korean journal of critical care medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Evaluation and Validation of Four Scoring Systems: the APACHE IV, SAPS III, MPM0 II, and ICMM in Critically Ill Cancer Patients.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Jae Woo ChoiDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Cheongju St. Mary's Hospital, Cheongju, Korea.ORCID 0000-0002-0483-1499
Young Sun ParkDepartment of Nursing Care, Chungnam National University Hospital, Daejeon, Korea.ORCID 0000-0003-3850-5090
Young Seok LeeDivision of Pulmonology and Critical Care Medicine, Department of Internal Medicine, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Korea.ORCID 0000-0002-0144-2033
Yeon Hee ParkDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Chungnam National University Hospital, Chungnam National University College of Medicine, Daejeon, Korea.ORCID 0000-0001-9537-1530
Chaeuk ChungDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Chungnam National University Hospital, Chungnam National University College of Medicine, Daejeon, Korea.ORCID 0000-0002-3978-0484
Dong Il ParkDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Chungnam National University Hospital, Chungnam National University College of Medicine, Daejeon, Korea.ORCID 0000-0001-7329-1724
In Sun KwonClinical Trial Center, Chungnam National University Hospital, Daejeon, Korea.ORCID 0000-0002-1723-436X
Ju Sang LeeDepartment of Nursing Care, Chungnam National University Hospital, Daejeon, Korea.ORCID 0000-0002-2883-6091
Na Eun MinDepartment of Nursing Care, Chungnam National University Hospital, Daejeon, Korea.ORCID 0000-0001-6252-8140
Jeong Eun ParkDepartment of Nursing Care, Chungnam National University Hospital, Daejeon, Korea.ORCID 0000-0002-6617-1940
Sang Hoon YooDivision of Pulmonology, Department of Internal Medicine, Chamjoeun Hospital, Gwangju, Korea.ORCID 0000-0002-0689-4637
Gyu Rak ChonDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Cheongju St. Mary's Hospital, Cheongju, Korea.ORCID 0000-0003-4713-9213
Young Hoon SulDepartment of Surgery, Chungbuk National University College of Medicine, Cheongju, Korea.ORCID 0000-0003-3184-3396
Jae Young MoonDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Chungnam National University Hospital, Chungnam National University College of Medicine, Daejeon, Korea.ORCID 0000-0001-8724-6289

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Acute Physiology and Chronic Health Evaluation (APACHE) II model has been widely used in Korea. However, there have been few studies on the APACHE IV model in Korean intensive care units (ICUs). The aim of this study was to compare the ability of APACHE IV and APACHE II in predicting hospital mortality, and to investigate the ability of APACHE IV as a critical care triage criterion.

methodsThe study was designed as a prospective cohort study. Measurements of discrimination and calibration were performed using the area under the receiver operating characteristic curve (AUROC) and the Hosmer-Lemeshow goodness-of-fit test respectively. We also calculated the standardized mortality ratio (SMR).

resultsThe APACHE IV score, the Charlson Comorbidity index (CCI) score, acute respiratory distress syndrome, and unplanned ICU admissions were independently associated with hospital mortality. The calibration, discrimination, and SMR of APACHE IV were good (H = 7.67, P = 0.465; C = 3.42, P = 0.905; AUROC = 0.759; SMR = 1.00). However, the explanatory power of an APACHE IV score >93 alone on hospital mortality was low at 44.1%. The explanatory power was increased to 53.8% when the hospital mortality was predicted using a model that considers APACHE IV >93 scores, medical admission, and risk factors for CCI >3 coincidentally. However, the discriminative ability of the prediction model was unsatisfactory (C index <0.70).

conclusionsThe APACHE IV presented good discrimination, calibration, and SMR for hospital mortality.

Indexed as

APACHE IVcalibrationdiscriminationintensive care unitstriage.

Identifiers

PMID31723646
PMCPMC6786733

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.