Evidence map›Paper›PMID 31723594›Full record

ArticleACS biomaterials science & engineering2019

Pleural Effusion Aspirate for use in 3D Lung Cancer Modeling and Chemotherapy Screening.

Andrea Mazzocchi, Mahesh Devarasetty, Samuel Herberg, William J Petty, Frank Marini, Lance Miller, Gregory Kucera, David K Dukes, Jimmy Ruiz, Aleksander Skardal and 1 more

Abstract read
In one paragraph

Article in ACS biomaterials science & engineering, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 84 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Andrea MazzocchiWake Forest Institute for Regenerative Medicine, Wake Forest School of Medicine, 391 Technology Way, Winston-Salem, NC, 27101, USA.
Mahesh DevarasettyWake Forest Institute for Regenerative Medicine, Wake Forest School of Medicine, 391 Technology Way, Winston-Salem, NC, 27101, USA.
Samuel HerbergCurrent address: SUNY Upstate Medical University, 505 Irving Avenue, Syracuse, NY 13210.
William J PettyDepartment of Cancer Biology, Wake Forest School of Medicine, 1 Medical Center Boulevard, Winston-Salem, NC, 27157, USA.
Frank MariniWake Forest Institute for Regenerative Medicine, Wake Forest School of Medicine, 391 Technology Way, Winston-Salem, NC, 27101, USA.
Lance MillerDepartment of Cancer Biology, Wake Forest School of Medicine, 1 Medical Center Boulevard, Winston-Salem, NC, 27157, USA.
Gregory KuceraDepartment of Cancer Biology, Wake Forest School of Medicine, 1 Medical Center Boulevard, Winston-Salem, NC, 27157, USA.
David K DukesCurrent address: Alabama College of Osteopathic Medicine, 445 Health Sciences Blvd, Dothan, AL 36303, USA.
Jimmy RuizDepartment of Cancer Biology, Wake Forest School of Medicine, 1 Medical Center Boulevard, Winston-Salem, NC, 27157, USA.
Aleksander SkardalWake Forest Institute for Regenerative Medicine, Wake Forest School of Medicine, 391 Technology Way, Winston-Salem, NC, 27101, USA.
Shay SokerWake Forest Institute for Regenerative Medicine, Wake Forest School of Medicine, 391 Technology Way, Winston-Salem, NC, 27101, USA.
Forest Institute · USAtrium Health Wake Forest Baptist · US

Funding

Tumor Tissue CoreP30CA012197 · NCI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Ruben A. Mesa · 1985 to 2026
$55.4M
Bioengineered Lung Tumor Organoids For Development Of Personalized MedicineR33CA202822 · NCI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI SOKER, SHAY · 2016 to 2018
$1.2M
NCI NIH HHS P30 CA012197NCI NIH HHS R33 CA202822
6 · The paper itself

Abstract

Lung cancer is the leading cause of cancer-related death worldwide yet

Indexed as

3D culturechemotherapydisease modelingpleural effusion

Identifiers

PMID31723594
PMCPMC6853614
OpenAlexW2921648992

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.