ArticleTherapeutic advances in musculoskeletal disease2019
Mortality risk prediction in lupus patients complicated with invasive infection in the emergency department: LUPHAS score.
Article in Therapeutic advances in musculoskeletal disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Observational
- Characteristics of patients with initial diagnosis of systemic lupus erythematosus in emergency department and their outcomes: a retrospective single-center study.Clinical rheumatology · 2024Article
- Major Infections of Newly Diagnosed Childhood-Onset Systemic Lupus Erythematosus.Journal of multidisciplinary healthcare · 2023Article
- Sepsis Mortality Is high in Patients With Connective Tissue Diseases Admitted to the Intensive Care Unit (ICU).Journal of intensive care medicine · 2022Article
- All-cause and cause-specific mortality in systemic lupus erythematosus: a population-based study.Rheumatology (Oxford, England) · 2021Article
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Authors and funding
10 authors.
Funding
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Abstract
backgroundInfection remains a major cause of morbidity and mortality in patients with systemic lupus erythematosus (SLE). This study aimed to establish a clinical prediction model for the 3-month all-cause mortality of invasive infection events in patients with SLE in the emergency department.
methodsSLE patients complicated with invasive infection admitted into the emergency department were included in this study. Patient's demographic, clinical, and laboratory characteristics on admission were retrospectively collected as baseline data and compared between the deceased and the survivors. Independent predictors were identified by multivariable logistic regression analysis. A prediction model for all-cause mortality was established and evaluated by receiver operating characteristic (ROC) curve analysis.
resultsA total of 130 eligible patients were collected with a cumulative 38.5% 3-month mortality. Lymphocyte count <800/ul, urea >7.6mmol/l, maximum prednisone dose in the past ⩾60 mg/d, quick Sequential Organ Failure Assessment (q
conclusionsBased on a large emergency cohort of lupus patients complicated with invasive infection, the LUPHAS score was established to predict the short-term all-cause mortality, which could be a promising applicable tool for risk stratification in clinical practice.
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