ArticleScientific reports2019
Early Life Trauma Has Lifelong Consequences for Sleep And Behavior.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
24 citing papers in PubMed.
- Associations between early-life mental health and abnormal sleep duration in midlife: findings from a prospective cohort study in Great Britain.European journal of epidemiology · 2026Article
- Time-Dynamic analysis of sex-specific NREM sleep disturbance induced by social isolation among adolescent mice.Translational psychiatry · 2026Article
- Exploration of wearable sensor measures associated with panic attacks differs across mental health conditions.Frontiers in digital health · 2026Article
- Dream Patterns in Patients with Acute Myocardial Infarction: Data from the STEP-IN-AMI Trial.Journal of clinical medicine · 2025Article
- Early life adversity and adult attention-deficit/hyperactivity disorder (ADHD): Pathways to persistence and adult susceptibility.Neuroscience and biobehavioral reviews · 2025Review
- Building a social brain: Cells, circuits and behavior across the lifespan.Neurobiology of stress · 2025Review
- The lateral habenula integrates age and experience to promote social transitions in developing rats.Cell reports · 2024Article
- Developmental alcohol exposure is exhausting: Sleep and the enduring consequences of alcohol exposure during development.Neuroscience and biobehavioral reviews · 2024Review
- The lateral habenula integrates age and experience to promote social transitions in developing rats.bioRxiv : the preprint server for biology · 2024Article
- Reported history of childhood trauma, mentalizing deficits, and hypersomnia in adulthood: A mediational analysis in a nonclinical sample.Brain and behavior · 2024Article
- Prenatal alcohol exposure and early-life adversity: A translational perspective for dissecting compounding impacts.Alcohol, clinical & experimental research · 2023Article
- Homeostatic NREM sleep and salience network function in adult mice exposed to ethanol during development.Frontiers in neuroscience · 2023Article
- The Nucleus Accumbens CRH-CRHR1 System Mediates Early-Life Stress-Induced Sleep Disturbance and Dendritic Atrophy in the Adult Mouse.Neuroscience bulletin · 2023Article
- Somatostatin neuron contributions to cortical slow wave dysfunction in adult mice exposed to developmental ethanol.Frontiers in neuroscience · 2023Article
- Chronic insomnia: are patients also suffering from PTSD symptoms?Frontiers in sleep · 2023Article
- Childhood trauma and gender: Synergistic and additive effects on sleep in healthy young adults.Sleep health · 2022Article
- Dream recall frequency and psychosomatics.Acta bio-medica : Atenei Parmensis · 2022Article
- Sleep disorders mediate the link between childhood trauma and depression severity in children and adolescents with depression.Frontiers in psychiatry · 2022Article
- Rodent models of early adversity: Impacts on developing social behavior circuitry and clinical implications.Frontiers in behavioral neuroscience · 2022Review
- Postpartum scarcity-adversity disrupts maternal behavior and induces a hypodopaminergic state in the rat dam and adult female offspring.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Sleep quality varies widely across individuals, especially during normal aging, with impaired sleep contributing to deficits in cognition and emotional regulation. Sleep can also be impacted by a variety of adverse events, including childhood adversity. Here we examined how early life adverse events impacted later life sleep structure and physiology using an animal model to test the relationship between early life adversity and sleep quality across the life span. Rat pups were exposed to an Adversity-Scarcity model from postnatal day 8-12, where insufficient bedding for nest building induces maternal maltreatment of pups. Polysomnography and sleep physiology were assessed in weaning, early adult and older adults. Early life adversity induced age-dependent disruptions in sleep and behavior, including lifelong spindle decreases and later life NREM sleep fragmentation. Given the importance of sleep in cognitive and emotional functions, these results highlight an important factor driving variation in sleep, cognition and emotion throughout the lifespan that suggest age-appropriate and trauma informed treatment of sleep problems.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.