Evidence map›Paper›PMID 31723166›Full record

ArticleScientific reports2019

A strategy for quality evaluation of salt-treated Apocyni Veneti Folium and discovery of efficacy-associated markers by fingerprint-activity relationship modeling.

Cuihua Chen, Jiali Chen, Jingjing Shi, Shuyu Chen, Hui Zhao, Ying Yan, Yucui Jiang, Ling Gu, Feiyan Chen, Xunhong Liu

Abstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Cuihua ChenCollege of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, China.ORCID http://orcid.org/0000-0001-7722-2160
Jiali ChenCollege of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
Jingjing ShiCollege of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
Shuyu ChenCollege of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
Hui ZhaoCollege of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
Ying YanCollege of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
Yucui JiangSchool of Basic Medicine, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
Ling GuSchool of Basic Medicine, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
Feiyan ChenSchool of Basic Medicine, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
Xunhong LiuCollege of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, China. liuxunh1959@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, a fingerprint-activity relationship between chemical fingerprints and hepatoprotective activity was established to evaluate the quality of salt-treated Apocyni Veneti Folium (AVF). Characteristic fingerprints of AVF samples exposed to different concentrations of salt were generated by ultrafast liquid chromatography tandem triple time-of-flight mass/mass spectrometry (UFLC-Triple TOF-MS/MS), and a similarity analysis was performed based on common characteristic peaks by hierarchical clustering analysis (HCA). Then, the hepatoprotective activity of AVF against CCl

Indexed as

AnimalsApocynumBiomarkersCarbon TetrachlorideChemical and Drug Induced Liver InjuryChromatography, High Pressure LiquidFlavonoidsLiverMaleMetabolomeMiceMice, Inbred ICRPlant ExtractsPlant LeavesQuality ControlSodium ChlorideBiomarkersCarbon TetrachlorideFlavonoidsPlant ExtractsSodium Chloride

Identifiers

PMID31723166
PMCPMC6853957

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.