Evidence map›Paper›PMID 31723039›Full record

ArticleScience translational medicine2019

Targeting redox heterogeneity to counteract drug tolerance in replicating

Richa Mishra, Sakshi Kohli, Nitish Malhotra, Parijat Bandyopadhyay, Mansi Mehta, MohamedHusen Munshi, Vasista Adiga, Vijay Kamal Ahuja, Radha K Shandil, Raju S Rajmani and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Science translational medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed
8.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

66 citing papers in PubMed, 115 citations in OpenAlex.

  1. A universal consuming endogenous HBioactive materials · 2027
    Article
  2. Article
  3. MakingCell insight · 2026
    Review
  4. A Pilot Proteomics Analysis ofInternational journal of molecular sciences · 2026
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Beyond culturability: VBNC-like and differentially culturableFrontiers in cellular and infection microbiology · 2026
    Review
  11. Review
  12. Article
  13. Genetic determinants ofMicrobiology spectrum · 2025
    Article
  14. Review
  15. Article
  16. Chemical genetic interactions elucidate pathways controlling tuberculosis antibiotic efficacy during infection.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  17. Article
  18. Article
  19. Article
  20. Review

6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Richa MishraDepartment of Microbiology and Cell Biology, Indian Institute of Science, Bangalore 560012, India.ORCID 0000-0003-2735-6894
Sakshi KohliDepartment of Microbiology and Cell Biology, Indian Institute of Science, Bangalore 560012, India.ORCID 0000-0002-1444-584X
Nitish MalhotraNational Centre for Biological Sciences (NCBS), Tata Institute of Fundamental Research (TIFR), Bangalore 560065, India.ORCID 0000-0001-8580-9623
Parijat BandyopadhyayDepartment of Microbiology and Cell Biology, Indian Institute of Science, Bangalore 560012, India.ORCID 0000-0002-9666-7445
Mansi MehtaDepartment of Microbiology and Cell Biology, Indian Institute of Science, Bangalore 560012, India.
MohamedHusen MunshiDepartment of Microbiology and Cell Biology, Indian Institute of Science, Bangalore 560012, India.ORCID 0000-0002-2764-5322
Vasista AdigaCentre for Infectious Disease Research, Indian Institute of Science, Bangalore 560012, India.ORCID 0000-0002-6996-4786
Vijay Kamal AhujaFoundation for Neglected Disease Research, Bangalore 560065, India.
Radha K ShandilFoundation for Neglected Disease Research, Bangalore 560065, India.ORCID 0000-0002-0908-1340
Raju S RajmaniCentre for Infectious Disease Research, Indian Institute of Science, Bangalore 560012, India.
Aswin Sai Narain SeshasayeeNational Centre for Biological Sciences (NCBS), Tata Institute of Fundamental Research (TIFR), Bangalore 560065, India.
Amit SinghDepartment of Microbiology and Cell Biology, Indian Institute of Science, Bangalore 560012, India. asingh@iisc.ac.in.ORCID 0000-0001-6761-1664
Indian Institute of Science Bangalore · INFoundation for Neglected Disease Research · INTata Institute of Fundamental Research · IN

Funding

DBT-Wellcome Trust India Alliance IA/S/16/2/502700Wellcome Trust
6 · The paper itself

Abstract

The capacity of

Indexed as

Drug Resistance, BacterialAcidsAnimalsAntitubercular AgentsBacterial ProteinsChloroquineCysteineDrug InteractionsDrug Resistance, Multiple, BacterialFemaleHIV InfectionsMacrophagesMice, Inbred BALB CMycobacterium tuberculosisOxidation-ReductionPhagosomesAcidsAntitubercular AgentsBacterial ProteinsChloroquineCysteine

Identifiers

PMID31723039
PMCPMC7212044
OpenAlexW2982849188

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.