Evidence map›Paper›PMID 31722596›Full record

ArticleJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2020

RNA sequencing reveals novel macrophage transcriptome favoring neurovascular plasticity after ischemic stroke.

Rongrong Wang, Yaan Liu, Qing Ye, Sulaiman H Hassan, Jingyan Zhao, Sicheng Li, Xiaoming Hu, Rehana K Leak, Marcelo Rocha, Lawrence R Wechsler and 2 more

Abstract read
In one paragraph

Article in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed.

  1. Article
  2. Monocyte-derived macrophages and their roles in ischemic stroke.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2026
    Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Neural repair mechanisms after ischemic stroke.Inflammation and regeneration · 2025
    Review
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Oxygen-Glucose Deprived Peripheral Blood Mononuclear Cells Protect Against Ischemic Stroke.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2023
    Article
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Rongrong WangDepartment of Neurology, Pittsburgh Institute of Brain Disorders & Recovery, University of Pittsburgh, Pittsburgh, PA, USA.
Yaan LiuDepartment of Neurology, Pittsburgh Institute of Brain Disorders & Recovery, University of Pittsburgh, Pittsburgh, PA, USA.
Qing YeDepartment of Neurology, Pittsburgh Institute of Brain Disorders & Recovery, University of Pittsburgh, Pittsburgh, PA, USA.
Sulaiman H HassanDepartment of Neurology, Pittsburgh Institute of Brain Disorders & Recovery, University of Pittsburgh, Pittsburgh, PA, USA.
Jingyan ZhaoDepartment of Neurology, Pittsburgh Institute of Brain Disorders & Recovery, University of Pittsburgh, Pittsburgh, PA, USA.
Sicheng LiDepartment of Neurology, Pittsburgh Institute of Brain Disorders & Recovery, University of Pittsburgh, Pittsburgh, PA, USA.
Xiaoming HuDepartment of Neurology, Pittsburgh Institute of Brain Disorders & Recovery, University of Pittsburgh, Pittsburgh, PA, USA.
Rehana K LeakGraduate School of Pharmaceutical Sciences, School of Pharmacy, Duquesne University, Pittsburgh, PA, USA.
Marcelo RochaDepartment of Neurology, UPMC Stroke Institute, University of Pittsburgh, Pittsburgh, PA, USA.
Lawrence R WechslerDepartment of Neurology, UPMC Stroke Institute, University of Pittsburgh, Pittsburgh, PA, USA.
Jun ChenDepartment of Neurology, Pittsburgh Institute of Brain Disorders & Recovery, University of Pittsburgh, Pittsburgh, PA, USA.
Yejie ShiDepartment of Neurology, Pittsburgh Institute of Brain Disorders & Recovery, University of Pittsburgh, Pittsburgh, PA, USA.ORCID 0000-0001-7502-9201

Funding

American Heart Association-American Stroke Association 17SDG33630130
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsBrainCell MovementCerebrovascular CirculationIschemic StrokeMacrophagesMice, Inbred C57BLMice, KnockoutMonocytesNeovascularization, PhysiologicNeurogenesisNeuronal PlasticityPPAR gammaSequence Analysis, RNATranscriptomePPAR gammaAngiogenesisfluorescence-activated cell sortingfocal cerebral ischemianeurogenesisPPARγ

Identifiers

PMID31722596
PMCPMC7168800

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.