Evidence map›Paper›PMID 31721763›Full record

ArticlePloS one2019

Incidence of colorectal cancer in Eritrea: Data from the National Health Laboratory, 2011-2017.

Lidia Biniam Medhin, Oliver Okoth Achila, Adiam Tesfamariam Abrham, Biniam Efrem, Kibrom Hailu, Daniel Mebrahtu Abraha, Luwam Gilazghi, Alay Meresie, Salih Mohammed Said

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Lidia Biniam MedhinPathology, National Health Laboratory, Asmara, Eritrea.ORCID 0000-0002-2438-5588
Oliver Okoth AchilaClinical Laboratory Sciences, Orotta School of Medicine and Health Sciences, Asmara, Eritrea.
Adiam Tesfamariam AbrhamClinical Laboratory Sciences, Orotta School of Medicine and Health Sciences, Asmara, Eritrea.
Biniam EfremClinical Laboratory Sciences, Orotta School of Medicine and Health Sciences, Asmara, Eritrea.
Kibrom HailuPathology, National Health Laboratory, Asmara, Eritrea.
Daniel Mebrahtu AbrahaHematology, National Health Laboratory, Asmara, Eritrea.
Luwam GilazghiImmunoserology, National Health Laboratory, Asmara, Eritrea.
Alay MeresieClinical Chemistry, National Health Laboratory, Asmara, Eritrea.
Salih Mohammed SaidMicrobiology, National Health Laboratory, Asmara, Eritrea.
University of Asmara · ER

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionRecent studies have reported a significant increase in the prevalence of colorectal cancer (CRC) in Sub-Saharan Africa (SSA). Further, several studies employing disparate modelling algorithms have projected a significant rise in the frequency of CRC cases in the region. However, lack of good quality data on multiple themes related to CRC including incidence, among others, continues to be a problem in the region. Therefore, this study was designed to collect data on the incidence of CRC in Eritrea.

methodsWe conducted a retrospective analysis using data captured between 2011 and 2017 at the National Health Laboratory (NHL) in Asmara, Eritrea.

results241 colorectal cases were identified in the Eritrean National Health Laboratory (NHL) database between 2011 and 2017. In the final analysis we included 94 patients confirmed cases giving an average of 18.8 patients per annum. The average age ± Standard deviation (SD) was 57.62 ± 17.14 with a male: female ratio of 58/36 (1: 1.61). The minimum and maximum age of the patients was 19 and 90 years, respectively. The rectum to colon ratio was 47/47 (1:1). The proportion of patients < 50 years in this cohort was significant. The age-standardized incidence rate (ASIR) in the study period was between 0.97 per 100 000 to 2.21 per 100 000. Similarly, the cumulative ASIR was 9.97 per 100 000. Analysis of trends did not reveal shifts over the study period (P<0.05). However, a strong correlation between incidence and age was established.

conclusionThis study suggests that the incidence of CRC in Eritrea is relatively low. A significant number of patients were less than 50 years of age. Even then it's our opinion that this study may underestimate the incidence of CRC.

Indexed as

AdultAgedAged, 80 and overColorectal NeoplasmsEritreaFemaleHumansIncidenceMaleMiddle AgedRetrospective StudiesYoung Adult

Identifiers

PMID31721763
PMCPMC6853305
OpenAlexW2987395770

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.