ArticleCancer medicine2020
Treatment of advanced gallbladder cancer: A SEER-based study.
Article in Cancer medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.
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Who cites it
40 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Risk factor analysis and nomogram establishment and verification of brain astrocytoma patients based on SEER database.Scientific reports · 2023Trial
- Association of surgical extent with survival in locally advanced gallbladder cancer based on propensity score matching.Scientific reports · 2026Article
- The B7 family subgroup reflects tumor cell heterogeneity and patient post-operative prognosis in gallbladder cancer.Biology direct · 2026Article
- Performance of major liver resection for gallbladder cancer-a western retrospective single center cohort study.Hepatobiliary surgery and nutrition · 2025Article
- Establishment and validation of a novel prognostic nomogram for gallbladder cancer patients.European journal of medical research · 2025Article
- Nomogram for predicting survival in breast cancer with lung metastasis based on SEER data.Translational cancer research · 2025Article
- Structure based multi-targeted screening, docking, DFT and simulation of anticancer natural compounds against gallbladder cancer.In silico pharmacology · 2025Article
- Explainable machine learning for predicting distant metastases in renal cell carcinoma patients: a population-based retrospective study.Frontiers in medicine · 2025Article
- The association of preoperative radiotherapy and surgery for AJCC stage I-III rectal adenocarcinoma: a population-based study.BMC surgery · 2024Article
- Comparison of treatment models for single primary advanced gallbladder cancer.Frontiers in immunology · 2024Article
- Isoalantolactone suppresses gallbladder cancer progression via inhibiting the ERK signalling pathway.Pharmaceutical biology · 2023Article
- Article
- Comparative Survival Benefits of Surgery and Adjuvant Chemotherapy in Neuroendocrine Carcinoma of the Gallbladder: A Population-Based Study with Insight into Future Personalized Therapeutic Approach.Journal of personalized medicine · 2023Article
- Article
- Article
- GBCdb: RNA expression landscapes and ncRNA-mRNA interactions in gallbladder carcinoma.BMC bioinformatics · 2023Article
- Treatment Patterns and Survival in Locally Advanced or Metastatic Biliary Tract Cancer Using SEER Medicare Data.Gastro hep advances · 2023Article
- A machine learning-based model for predicting distant metastasis in patients with rectal cancer.Frontiers in oncology · 2023Article
- Anticancer Drugs Compared to No Anticancer Drugs in Patients with Advanced Hepatobiliary Cancer: A Mapping Review and Evidence Gap Map.Clinical epidemiology · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe treatment of advanced gallbladder cancer (GBC) remains controversial. Therefore, the purpose of this study was to explore treatment choices for advanced GBC.
methodsWe identified four different treatments from the surveillance, epidemiology, and end results (SEER) database: surgery, chemotherapy (CT), surgery and chemotherapy (Surgery + CT), and no surgery/no chemotherapy (No surgery/No CT). Kaplan-Meier method and Cox proportional hazards regression method were used to determine the risk factors for overall survival (OS) and cancer-specific survival (CSS). In addition, patients in AJCC stages III and IV stage were matched with 1:1 propensity score matching (PSM) for diagnosis age, race, marital status, histological type, tumor grade, and treatment pattern to decrease the possibility of selection bias.
resultsA total of 288 AJCC stage III patients and 4239 AJCC stage IV patients with advanced GBC were identified from the SEER database between 2004 and 2015. Treatment pattern was an independent risk factor for patients with advanced GBC. For all patient, AJCC stage III patients and AJCC stage IV patients, "Surgery + CT" treatment minimized the OS and CSS in advanced GBC patients. In addition, after the PSM analysis, the "Surgery + CT" treatment still significantly decreased patient OS and CSS.
conclusions"Surgery + CT" treatment can provide survival benefits for patients with advanced GBC. In addition, "Surgery + CT" treatment was not fully utilized and may further improve the survival rate of GBC patients.
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