Evidence map›Paper›PMID 31721359›Full record

ArticleStem cells (Dayton, Ohio)2020

A histone deacetylase 7-derived peptide promotes vascular regeneration via facilitating 14-3-3γ phosphorylation.

Junyao Yang, Ana Moraga, Jing Xu, Yue Zhao, Peiyi Luo, Ka Hou Lao, Andriana Margariti, Qiang Zhao, Wei Ding, Gang Wang and 10 more

Open access · hybridAbstract read
In one paragraph

Article in Stem cells (Dayton, Ohio), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. A novel nested geneGenes & diseases · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 7 institutions in 2 countries.

Junyao YangSchool of Cardiovascular Medicine and Sciences, King's College - London British Heart Foundation Centre of Excellence, Faculty of Life Science and Medicine, King's College London, London, UK.ORCID 0000-0003-3307-704X
Ana MoragaSchool of Cardiovascular Medicine and Sciences, King's College - London British Heart Foundation Centre of Excellence, Faculty of Life Science and Medicine, King's College London, London, UK.
Jing XuInstitute of Bioengineering, Queen Mary University of London, London, UK.
Yue ZhaoSchool of Cardiovascular Medicine and Sciences, King's College - London British Heart Foundation Centre of Excellence, Faculty of Life Science and Medicine, King's College London, London, UK.
Peiyi LuoSchool of Cardiovascular Medicine and Sciences, King's College - London British Heart Foundation Centre of Excellence, Faculty of Life Science and Medicine, King's College London, London, UK.
Ka Hou LaoSchool of Cardiovascular Medicine and Sciences, King's College - London British Heart Foundation Centre of Excellence, Faculty of Life Science and Medicine, King's College London, London, UK.
Andriana MargaritiCentre for Experimental Medicine, Queen's University Belfast, Belfast, UK.ORCID 0000-0001-9303-8371
Qiang ZhaoState Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Bioactive Materials, Ministry of Education, College of Life Sciences, Nankai University, Tianjin, People's Republic of China.
Wei DingInstitute of Bioengineering, Queen Mary University of London, London, UK.
Gang WangDepartment of Emergency Medicine, The Second Affiliated Hospital, Xi'an Jiaotong University, Xi'an, People's Republic of China.
Min ZhangSchool of Cardiovascular Medicine and Sciences, King's College - London British Heart Foundation Centre of Excellence, Faculty of Life Science and Medicine, King's College London, London, UK.
Lei ZhengSouthern Medical University, Guangzhou, People's Republic of China.
Zhongyi ZhangSchool of Cardiovascular Medicine and Sciences, King's College - London British Heart Foundation Centre of Excellence, Faculty of Life Science and Medicine, King's College London, London, UK.
Yanhua HuSchool of Cardiovascular Medicine and Sciences, King's College - London British Heart Foundation Centre of Excellence, Faculty of Life Science and Medicine, King's College London, London, UK.
Wen WangInstitute of Bioengineering, Queen Mary University of London, London, UK.
Lisong ShenDepartment of Clinical Laboratory, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.
Alberto SmithSchool of Cardiovascular Medicine and Sciences, King's College - London British Heart Foundation Centre of Excellence, Faculty of Life Science and Medicine, King's College London, London, UK.
Ajay M ShahSchool of Cardiovascular Medicine and Sciences, King's College - London British Heart Foundation Centre of Excellence, Faculty of Life Science and Medicine, King's College London, London, UK.
Qian WangSouthern Medical University, Guangzhou, People's Republic of China.
Lingfang ZengSchool of Cardiovascular Medicine and Sciences, King's College - London British Heart Foundation Centre of Excellence, Faculty of Life Science and Medicine, King's College London, London, UK.ORCID 0000-0002-0390-4561
King's College London · GBQueen Mary University of London · GBShanghai Jiao Tong University · CNSouthern Medical University · CNNankai University · CNQueen's University Belfast · GBSecond Affiliated Hospital of Xi'an Jiaotong University · CN

Funding

British Heart Foundation CH/1999001/11735British Heart Foundation FS/15/23/31435British Heart Foundation PG/15/3/31226British Heart Foundation PG/16/8/31985British Heart Foundation PG/17/39/33027British Heart Foundation PG/18/29/33731
6 · The paper itself

Abstract

Histone deacetylase 7 (HDAC7) plays a pivotal role in the maintenance of the endothelium integrity. In this study, we demonstrated that the intron-containing Hdac7 mRNA existed in the cytosol and that ribosomes bound to a short open reading frame (sORF) within the 5'-terminal noncoding area of this Hdac7 mRNA in response to vascular endothelial growth factor (VEGF) stimulation in the isolated stem cell antigen-1 positive (Sca1

Indexed as

AnimalsCell ProliferationHistone DeacetylasesHumansMaleMiceNeovascularization, PhysiologicPhosphorylationSignal TransductionHistone Deacetylaseshistone deacetylase 7peptidephosphorylationshort open reading framevascular progenitor cell

Identifiers

PMID31721359
PMCPMC7187271
OpenAlexW2988150882

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.