ArticleMagnetic resonance in medicine2020
Intra-session and inter-subject variability of 3D-FID-MRSI using single-echo volumetric EPI navigators at 3T.
Article in Magnetic resonance in medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 40 citations in OpenAlex.
- Advanced methods in deuterium metabolic imaging.Magma (New York, N.Y.) · 2026Review
- Correcting motion-related BScientific reports · 2026Article
- Constructing the human brain metabolic connectome with MR spectroscopic imaging reveals cerebral biochemical organization.Nature communications · 2025Article
- Accelerated Navigator for Rapid ∆BNMR in biomedicine · 2025Article
- From a Voxel to Maps: A Comparative Study of sLASER SVS and 3D-CRT-FID-MRSI at 3 T and 7 T.medRxiv : the preprint server for health sciences · 2025Article
- Rosette Spectroscopic Imaging for Whole-Brain Slab Metabolite Mapping at 7T: Acceleration Potential and Reproducibility.Human brain mapping · 2025Article
- Accelerated 3D metabolite TMagnetic resonance in medicine · 2024Article
- BMagnetic resonance in medicine · 2024Article
- Fast high-resolution prospective motion correction for single-voxel spectroscopy.Magnetic resonance in medicine · 2024Article
- Test-Retest Reproducibility of Reduced-Field-of-View Density-Weighted CRT MRSI at 3T.Tomography (Ann Arbor, Mich.) · 2024Article
- Reproducibility of 3D MRSI for imaging human brain glucose metabolism using direct (NeuroImage · 2023Article
- Article
- Reproducibility of 3D MRSI for imaging human brain glucose metabolism using direct (medRxiv : the preprint server for health sciences · 2023Article
- Whole-brain high-resolution metabolite mapping with 3D compressed-sensing SENSE low-rankNMR in biomedicine · 2022Article
- Inter-subject stability and regional concentration estimates of 3D-FID-MRSI in the human brain at 7 T.NMR in biomedicine · 2021Article
- High-resolution metabolic mapping of the cerebellum using 2D zoom magnetic resonance spectroscopic imaging.Magnetic resonance in medicine · 2021Article
- Motion correction methods for MRS: experts' consensus recommendations.NMR in biomedicine · 2021Article
- Real-time motion and retrospective coil sensitivity correction for CEST using volumetric navigators (vNavs) at 7T.Magnetic resonance in medicine · 2021Article
- ECLIPSE utilizing gradient-modulated offset-independent adiabaticity (GOIA) pulses for highly selective human brain proton MRSI.NMR in biomedicine · 2021Article
- Intra-session and inter-subject variability of 3D-FID-MRSI using single-echo volumetric EPI navigators at 3T.Magnetic resonance in medicine · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 3 institutions in 2 countries.
Funding
Abstract
purposeIn this study, we demonstrate the first combination of 3D FID proton MRSI and spatial encoding via concentric-ring trajectories (CRTs) at 3T. FID-MRSI has many benefits including high detection sensitivity, in particular for J-coupled metabolites (e.g., glutamate/glutamine). This makes it highly attractive, not only for clinical, but also for, potentially, functional MRSI. However, this requires excellent reliability and temporal stability. We have, therefore, augmented this 3D-FID-MRSI sequence with single-echo, imaging-based volumetric navigators (se-vNavs) for real-time motion/shim-correction (SHMOCO), which is 2× quicker than the original double-echo navigators (de-vNavs), hence allowing more efficient integration also in short-TR sequences.
methodsThe tracking accuracy (position and B
resultsPhantom and in vivo scans showed highly consistent tracking performance for se-vNavs compared to the original de-vNavs, but lower frequency drift. Up to ~30% better intra-subject CVs were obtained for SHMOCO (P < 0.05), with values of 9.3/6.9/6.5/7.8% over the full VOI for Glx/tNAA/tCho/m-Ins ratios to tCr. ICCs were good-to-high (91% for Glx/tCr in motor cortex), whereas the inter-subject variability was ~11-19%.
conclusionReal-time motion/shim corrected 3D-FID-MRSI with time-efficient CRT-sampling at 3T allows reliable, high-resolution metabolic imaging that is fast enough for clinical use and even, potentially, for functional MRSI.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.