Evidence map›Paper›PMID 31721064›Full record

ArticleObesity surgery2020

The Influence of Persistent Organic Pollutants on Thyroidal, Reproductive and Adrenal Hormones After Bariatric Surgery.

Aina Jansen, Jens Petter Berg, Ole Klungsøyr, Mette Helen Bjørge Müller, Jan Ludvig Lyche, Jan Olav Aaseth

Abstract read
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In one paragraph

Article in Obesity surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 3 pooled it
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 3 syntheses or guidelines pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pollution, stress response, and obesity: A systematic review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2025
    Pooled it
  4. Article
  5. Article
  6. Genes · 2022
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Aina JansenDepartment of Surgery, Innlandet Hospital Trust, Gjøvik, Norway. aina.jansen@sykehuset-innlandet.no.ORCID 0000-0001-9669-5887
Jens Petter BergDepartment of Medical Biochemistry, Oslo University Hospital, Oslo, Norway.
Ole KlungsøyrCentre for Biostatistics and Epidemiology, Section for Treatment Research, Department for Research and Education, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.
Mette Helen Bjørge MüllerDepartment of Food Safety and Infection Biology, Norwegian University of Life Sciences (NMBU), Oslo, Norway.
Jan Ludvig LycheDepartment of Food Safety and Infection Biology, Norwegian University of Life Sciences (NMBU), Oslo, Norway.
Jan Olav AasethResearch Department, Innlandet Hospital Trust, Brumunddal, Norway.
Innlandet Hospital Trust · NONorwegian University of Life Sciences · NOOslo University Hospital · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPersistent organic pollutants (POPs) including organochlorine pesticides, polychlorinated biphenyls (PCBs), and per- and polyfluoroalkylated substances (PFASs) are suspected endocrine disruptors.

aimTo evaluate the associations between POPs and thyroidal, reproductive, and adrenal hormones in a study population treated with bariatric surgery.

methodsBlood samples from a cohort of 63 participants before and 1 year after bariatric surgery were analyzed for 16 lipophilic POPs, 17 PFASs, and thyroidal, reproductive, and adrenal hormones. Participants reporting relevant medical conditions or interfering medication were excluded, and plausible confounders were corrected for in multiple regression analyses.

resultsFree thyroxine (fT

conclusionThe results suggest that POPs may have an influence on the hypothalamic-pituitary-thyroid (HPT) and the hypothalamic-pituitary-gonadal (HPG) axes after bariatric surgery. Because of small sample sizes and discrepancy in the sampling time points pre- and postoperatively, the observed hormonal impacts of POPs must be interpreted as associative and not causative. Further studies are needed to confirm the findings.

Indexed as

Bariatric SurgeryObesity, MorbidEnvironmental ExposureFemaleHumansMalePersistent Organic PollutantsThyroid GlandPersistent Organic PollutantsBariatric surgeryCortisolEndocrine disrupting chemicalsObesityReproductive hormonesThyroid hormones

Identifiers

PMID31721064
OpenAlexW2984974437

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.