Evidence map›Paper›PMID 31720793›Full record

ArticleWorld journal of surgery2020

Incidence and Risk Factors for Severity of Postoperative Ileus After Colorectal Surgery: A Prospective Registry Data Analysis.

A Venara, H Meillat, E Cotte, M Ouaissi, E Duchalais, C Mor-Martinez, A Wolthuis, J M Regimbeau, S Ostermann, J F Hamel and 3 more

Erratum issuedAbstract read
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In one paragraph

Article in World journal of surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Pooled it
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  11. High-pressure COUpdates in surgery · 2021
    Article
  12. Targets for Intervention? Preoperative Predictors of Postoperative Ileus After Colorectal Surgery in an Enhanced Recovery Protocol.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2021
    Article
  13. Article
  14. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 11 institutions in 3 countries.

A VenaraFaculty of Medicine of Angers, Angers, France. auvenara@yahoo.fr.ORCID http://orcid.org/0000-0003-1539-4797
H MeillatInstitut Paoli-Calmette, 232 Boulevard de Sainte Marguerite, 13009, Marseille, France.
E CotteDepartment of Visceral Surgery, CHU Lyon, Centre Hospitalier Lyon-Sud, 69495, Pierre-Bénite Cedex, France.
M OuaissiDepartment of Visceral Surgery, CHU Tours, 2 Boulevard Tonnelé, 37000, Tours, France.
E DuchalaisUMR INSERM U1235, TENS, The Enteric Nervous System in Gut and Brain Disorders, Institut des Maladies de l'Appareil Digestif, 1, Rue Gaston Veil, 44035, Nantes, France.
C Mor-MartinezDepartment of Visceral Surgery, Clinique de l'Alliance, 1 Boulevard A Nobel, 37540, Saint Cyr Sur Loire, France.
A WolthuisDepartment of Abdominal Surgery, UZ Leuven, Herestraat 49, 3000, Leuven, Belgium.
J M RegimbeauDepartment of Visceral Surgery, CHU Amiens, Avenue Laennec, 80054, Amiens, France.
S OstermannHirslanden Clinique La Colline, Geneva, Switzerland.
J F HamelDepartment of Methodology and Biostatistics, CHU Angers, 4 Rue Larrey, 49933, Angers Cedex 9, France.
J JorisDepartment of Anesthesiology, CHU Liège, Domaine de Sart Tilman, Université de Liège, 4000, Liege, Belgium.
K SlimDepartment of Visceral Surgery, CHU Clermont-Ferrand, 63003, Clermont-Ferrand, France.
GRACE Collaborative Group For Ileus Study
Centre Hospitalier Universitaire de Clermont-Ferrand · FRCentre Hospitalier Universitaire d'Angers · FRCentre Hospitalier Universitaire Amiens-Picardie · FRUniversity of Liège · BEHirslanden Clinique La Colline · CHCentre Hospitalier Universitaire de Nantes · FRInserm · FRCentre Hospitalier Universitaire de Tours · FRInstitut Paoli-Calmettes · FRUniversitair Ziekenhuis Leuven · BEUniversité Claude Bernard Lyon 1 · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDefining severe postoperative ileus in terms of consequences could help physicians standardize the management of this condition. The recently described classification based on consequences requires further investigation. The aim of this study was to obtain a snapshot of postoperative ileus in patients undergoing colorectal surgery within enhanced recovery programs and to identify factors associated with non-severe and severe postoperative ileus.

methodsThis prospective registry data analysis was conducted in 40 centers in five different countries. A total of 786 patients scheduled for colorectal surgery within enhanced recovery programs were included. The primary endpoint was the incidence rate of postoperative ileus as defined by Vather et al.

resultsA total of 121 patients experienced postoperative ileus (15.4%). Non-severe POI occurred in 48 patients (6.1%), and severe postoperative ileus occurred in 73 patients (9.3%). In multivariate analysis, the male gender and intra-abdominal complications were associated with severe postoperative ileus: odd ratio (OR) = 2.03 [95% confidence interval (CI) 1.14-3.59], p = 0.01 and OR = 3.60 [95% CI 1.75-7.40], p < 0.0001, respectively. Conversely, open laparotomy and urinary retention were associated with non-severe POI: OR = 3.03 [95% CI 1.37-6.72], p = 0.006 and OR = 2.70 [95% CI 0.89-8.23], p = 0.08, respectively.

conclusionsPostoperative ileus occurred in 15% of patients after colorectal surgery within enhanced recovery programs. For 60% of patients, this was considered severe. The physiopathology of these two entities could be different, severe POI being linked to intraabdominal complication, while non-severe POI being linked with risk factors for "primary" POI. The physician should pay attention to male patients having POI after colorectal surgery and look for features evocating intraabdominal complications.

Indexed as

AgedColonDigestive System Surgical ProceduresEnhanced Recovery After SurgeryFemaleHumansIleusIncidenceMaleMiddle AgedPatient AcuityPostoperative ComplicationsProspective StudiesRectumRegistriesRisk Factors

Identifiers

PMID31720793
OpenAlexW2988984065

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.