Evidence map›Paper›PMID 31720508›Full record

ArticleACS omega2019

Disorder-to-Order Markers of a Cyclic Hexapeptide Inspired from the Binding Site of Fertilin β Involved in Fertilization Process.

Belén Henández, Pauline Legrand, Sophie Dufay, Rabah Gahoual, Santiago Sanchez-Cortes, Sergei G Kruglik, Jean-Roch Fabreguettes, Jean-Philippe Wolf, Pascal Houzé, Mahmoud Ghomi

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Belén HenándezLaboratoire Matrice Extracellulaire et Dynamique Cellulaire (MEDyC), UMR 7369, Université de Reims, Faculté des Sciences, Moulin de la Housse, 51687 Reims Cedex 2, France.
Pauline LegrandUnité de Technologies Chimiques et Biologiques pour la Santé (UTCBS), CNRS UMR 8258-U1022, Faculté de Pharmacie Paris Descartes, Université Paris Descartes, 75006 Paris, France.
Sophie DufayAgence Générale des Equipements et Produits de Santé (AGEPS), Assistance Publique-Hôpitaux de Paris (AP-HP), 75005 Paris, France.
Rabah GahoualUnité de Technologies Chimiques et Biologiques pour la Santé (UTCBS), CNRS UMR 8258-U1022, Faculté de Pharmacie Paris Descartes, Université Paris Descartes, 75006 Paris, France.
Santiago Sanchez-CortesInstituto de Estructura de la Materia, IEM-CSIC, Serrano 121, 28006 Madrid, Spain.
Sergei G KruglikLaboratoire Jean Perrin, Sorbonne Université, CNRS UMR 8237, 75005 Paris, France.
Jean-Roch FabreguettesAgence Générale des Equipements et Produits de Santé (AGEPS), Assistance Publique-Hôpitaux de Paris (AP-HP), 75005 Paris, France.
Jean-Philippe WolfSorbonne Paris Cité, Université Paris Descartes, Faculté de Médecine, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Universitaire Paris Centre, Centre Hospitalier Universitaire (CHU) Cochin, Service d'Histologie-Embryologie-Biologie de la Reproduction, 75006 Paris, France.
Pascal HouzéUnité de Technologies Chimiques et Biologiques pour la Santé (UTCBS), CNRS UMR 8258-U1022, Faculté de Pharmacie Paris Descartes, Université Paris Descartes, 75006 Paris, France.
Mahmoud GhomiLaboratoire Matrice Extracellulaire et Dynamique Cellulaire (MEDyC), UMR 7369, Université de Reims, Faculté des Sciences, Moulin de la Housse, 51687 Reims Cedex 2, France.
Centre National de la Recherche Scientifique · FRAgence France-Presse · FRHôpital Necker-Enfants Malades · FRInstituto de Estructura de la Materia · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Synthetic peptides mimicking the binding site of fertilin β to its receptor, integrin α6β1, were shown to inhibit sperm-egg fusion when added to in vitro media. In contrast, the synthetic cyclic hexapeptide, cyclo(Cys

Identifiers

PMID31720508
PMCPMC6843708
OpenAlexW2981666726

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.