Evidence map›Paper›PMID 31720434›Full record

ArticleJournal of clinical tuberculosis and other mycobacterial diseases2019

Feasibility of a short message service (SMS) intervention to deliver tuberculosis testing results in peri-urban and rural Uganda.

Diana Babirye, Priya B Shete, Katherine Farr, Talemwa Nalugwa, Christopher Ojok, Mariam Nantale, Denis Oyuku, Irene Ayakaka, Achilles Katamba, J Lucian Davis and 4 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical tuberculosis and other mycobacterial diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 4 pooled it
5.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 4 syntheses or guidelines pooled it, 25 citations in OpenAlex.

  1. Pooled it
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  4. Pooled it
  5. Closing gaps through innovation in the tuberculosis pathology value chain.Journal of clinical tuberculosis and other mycobacterial diseases · 2026
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  17. Implementation science to improve the quality of tuberculosis diagnostic services in Uganda.Journal of clinical tuberculosis and other mycobacterial diseases · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 3 countries.

Diana BabiryeUganda Tuberculosis Implementation Research Consortium, Makerere University, P.O. Box 21696, Kampala, Uganda.
Priya B SheteUganda Tuberculosis Implementation Research Consortium, Makerere University, P.O. Box 21696, Kampala, Uganda.
Katherine FarrUganda Tuberculosis Implementation Research Consortium, Makerere University, P.O. Box 21696, Kampala, Uganda.
Talemwa NalugwaUganda Tuberculosis Implementation Research Consortium, Makerere University, P.O. Box 21696, Kampala, Uganda.
Christopher OjokUganda Tuberculosis Implementation Research Consortium, Makerere University, P.O. Box 21696, Kampala, Uganda.
Mariam NantaleUganda Tuberculosis Implementation Research Consortium, Makerere University, P.O. Box 21696, Kampala, Uganda.
Denis OyukuUganda Tuberculosis Implementation Research Consortium, Makerere University, P.O. Box 21696, Kampala, Uganda.
Irene AyakakaUganda Tuberculosis Implementation Research Consortium, Makerere University, P.O. Box 21696, Kampala, Uganda.
Achilles KatambaUganda Tuberculosis Implementation Research Consortium, Makerere University, P.O. Box 21696, Kampala, Uganda.
J Lucian DavisUganda Tuberculosis Implementation Research Consortium, Makerere University, P.O. Box 21696, Kampala, Uganda.
Diana NadungaNational Tuberculosis Reference Laboratory, Ministry of Health, Plot 106-1062 Butabika Road, Luzira, Kampala, Uganda.
Moses JolobaNational Tuberculosis Reference Laboratory, Ministry of Health, Plot 106-1062 Butabika Road, Luzira, Kampala, Uganda.
David MooreLondon School of Hygiene and Tropical Medicine, Keppel St, Bloomsbury, London WC1E 7HT, UK.
Adithya CattamanchiUganda Tuberculosis Implementation Research Consortium, Makerere University, P.O. Box 21696, Kampala, Uganda.
Makerere University · UGMinistry of Health · UGLondon School of Hygiene & Tropical Medicine · GBSan Francisco General Hospital · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
SIngle-saMPLE tuberculosis evaluation to facilitate linkage to care: The SIMPLE TB trialR01HL130192 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CATTAMANCHI, ADITHYA · 2016 to 2020
$3.2M
NCATS NIH HHS UL1 TR001863NHLBI NIH HHS R01 HL130192
6 · The paper itself

Abstract

backgroundPre-treatment loss to follow-up is common for patients diagnosed with tuberculosis (TB) in high-burden countries. Delivering test results by Short-Messaging-Service (SMS) is increasingly being considered as a solution, but there is limited information about its feasibility as a public health tool in low resourced settings.

objectiveWe sought to assess the feasibility of utilizing SMS technology to deliver TB test results during routine TB diagnostic evaluation in Uganda.

methodsWe conducted a single arm interventional pilot study at four community health centers in Uganda that referred sputum samples to a district hospital for GeneXpert-MTB/RIF (Xpert) testing (Cepheid, USA). Using existing GxAlert-software (SystemOne,USA), we set up an automated SMS platform to send Xpert results to patients and referring health centers. We assessed each step of the SMS delivery cascade for consecutive patients who presented to these four community health centers between December 2015 and March 2016 and underwent Xpert testing.

resultsOf 233 patients enrolled, 161 (69%) had phone numbers recorded on individual Xpert referral forms. Phone numbers were entered into Xpert device software in the correct format for 152 (94%) patients. GxAlert-software generated an automated SMS reporting Xpert results for 151 (99%) patients and delivered it successfully to mobile phone service providers for 145/151 (96%). Of the 123 patients reached by phone to determine receipt of test results, 114 (93%) confirmed SMS receipt. SMS-based delivery of Xpert results was verified for 114/233 (49%) patients overall. In contrast, phone calls to health centers confirmed that health centers received messages for 222/233 (95%) patients.

conclusionReporting Xpert results via automated SMS is technically feasible and results in approximately half of patients receiving their test results immediately. Additional research should be done to address process inefficiencies in order to maximize impact of this technology and link its successful utilization to improved patient outcomes.

Indexed as

Information and communication technologyMobile technologySMS

Identifiers

PMID31720434
PMCPMC6830162
OpenAlexW2952413232

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.