ArticleJournal of clinical tuberculosis and other mycobacterial diseases2019
Abnormalities suggestive of latent tuberculosis infection on chest radiography; how specific are they?
Article in Journal of clinical tuberculosis and other mycobacterial diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 11 citations in OpenAlex.
- Association of inactive pulmonary tuberculosis lesions with the risk of active disease development in the elderly: a population-based retrospective study.ERJ open research · 2025Article
- Calcified Lung Nodules: A Diagnostic Challenge in Clinical Daily Practice.Tomography (Ann Arbor, Mich.) · 2025Review
- Latent Tuberculosis Infection in Healthcare Workers: A Cross-Sectional Study from a Tertiary Hospital in Central Anatolia.Journal of clinical practice and research · 2024Article
- Acute miliary tuberculosis in pregnancy after in vitro fertilization and embryo transfer: a report of seven cases.BMC infectious diseases · 2021Article
- Impact of Positive Interferon-Gamma Release Assay on IVF-ET Pregnancy Outcomes in Infertile Patients With Untreated Prior Tuberculosis: A Prospective Cohort Study.Frontiers in medicine · 2021Article
- Tuberculosis in migrants - screening, surveillance and ethics.Pneumonia (Nathan Qld.) · 2020Review
- Reactivation of latent tuberculosis infection induced by cabazitaxel in a patient with prostate cancer: A case report.Medicine · 2019Article
- Radiological Signs of Latent Tuberculosis on Chest Radiography: A Systematic Review and Meta-Analysis.Open forum infectious diseases · 2019Article
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSeveral radiological features have been reported in association with latent tuberculosis infection (LTBI) but it has not been studied which are specific. The aim of this study was to evaluate allegedly characteristic abnormalities on chest radiography (CXR) in patients with LTBI compared to uninfected controls.
methodsFrom 236 patients tested with QuantiFERON-TB Gold In-Tube (QFT), the CXR was re-evaluated in a blinded fashion for fibrotic scarring, (non-)calcified nodules and pleural thickening. LTBI was defined as presence of a positive QFT result and/or positive tuberculin skin test result stratified by Bacille Calmette-Guérin-vaccination status.
resultsAny predefined abnormality of LTBI was observed in 116/236 (49.2%) patients, the frequency not being different between groups. However, the specificity for LTBI of a fibrotic scar ≥ 2 cm
conclusionOnly a fibrotic scar ≥ 2 cm
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