Evidence map›Paper›PMID 31720400›Full record

ArticleJournal of clinical tuberculosis and other mycobacterial diseases2018

Dynamics of tuberculosis in Wau, South Sudan during a period of armed conflict.

Caeser Sobe Jermano Boyong, Clovice Kankya, Muleme James, M Munyeme, A S Jubara, D Ndoboli, G Ekuka, A Muwonge

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical tuberculosis and other mycobacterial diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 4 countries.

Caeser Sobe Jermano BoyongDepartment of Clinical Studies University of Bahr El Ghazal, College of Veterinary Science, Wau South, Sudan.
Clovice KankyaDepartment of Biosecurity, Ecosystems and Veterinary Public health, College of Veterinary Medicine Animal Resources and Biosecurity, Makerere University, Uganda.
Muleme JamesDepartment of Biosecurity, Ecosystems and Veterinary Public health, College of Veterinary Medicine Animal Resources and Biosecurity, Makerere University, Uganda.
M MunyemeDepartment of Disease Control, The University of Zambia, School of Veterinary Medicine, Zambia.
A S JubaraDepartment of Surgery and Gynecology, University of Bahr El Ghazal-College of Veterinary Science-Wau.
D NdoboliCentral Diagnostic Laboratory, College of Veterinary Medicine, Makerere University, Uganda.
G EkukaNational Tuberculosis Referral Laboratory, Uganda, Kampala.
A MuwongeDivision of Genetics and Genomics, The Roslin Institute, The Royal (Dick) School of Veterinary Studies, College of Medicine and Veterinary studies, University of Edinburgh, Easter Bush, Midlothian, EH25 9RG, UK.
Makerere University · UGRoslin Institute · GBUniversity of Bahr El-Ghazal · SSUniversity of Zambia · ZM

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSouth Sudan has endured decades of armed conflict, with the most recent in 2016. This has left the health system and infrastructure overstretched by a myriad of infectious diseases like tuberculosis. Our study aimed at quantitatively and qualitatively documenting TB dynamics and challenges with access to health care during a period of civil unrest in Wau. MATERIALS &

methodsA cross sectional study was carried out between January and February 2016 at Wau Teaching Hospital (WTH). Sputum was randomly collected from 207 of the 1035 TB suspects and analyzed using Ziehl-Neelsen (ZN) and Fluorescent Microscopy (FM), Culture, Capilia MTBC Neo, and DST. The laboratory results and questionnaire metadata were used for descriptive statistics, logistic regression in R version 3.4.2. These results were presented along with results from a qualitative assessment of the situation at WTH.

resultsOf 207 TB suspects, 39 (18.8%) were positive on FM with bacilli growth on culture, later confirmed as

conclusionWe report a high prevalence of tuberculosis among patients who presented at WTH, with approximately 1 out of 5 individuals testing positive for tuberculosis. This is likely an underestimation given the challenges patients had to endure as they sought medical attention. Tuberculosis epidemiology is likely to be driven by individual and household factors, but further investigations are needed to fully understand the risk profile. The tools in use were adequate for TB diagnostics and we observed a remarkably low prevalence of drug resistance, a statistic that is worth preserving. We therefore call for action from all stakeholders.

Indexed as

Armed conflictSouth SudanTuberculosisWau

Identifiers

PMID31720400
PMCPMC6830182
OpenAlexW2884857665

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.