Evidence map›Paper›PMID 31720385›Full record

ArticleJournal of clinical tuberculosis and other mycobacterial diseases2018

Use of classification and regression tree (CART), to identify hemoglobin A1C (HbA

Josephine W Mburu, Leonard Kingwara, Magiri Ester, Nyerere Andrew

Abstract read
In one paragraph

Article in Journal of clinical tuberculosis and other mycobacterial diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Josephine W MburuNational Reference Tuberculosis Laboratory, MOH, Kenya.
Leonard KingwaraNational Reference Tuberculosis Laboratory, MOH, Kenya.
Magiri EsterJomo Kenyatta University of Agriculture and Technology (JKUAT), Kenya.
Nyerere AndrewJomo Kenyatta University of Agriculture and Technology (JKUAT), Kenya.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRifampin-based therapy potentially exacerbates glycemic control among TB patients who are already at high risk of hyperglycemia. This impacts negatively to the optimal care of TB- diabetes mellitus co-affected patients. Classification and regression tree (CART), a machine-learning algorithm impervious to statistical assumptions is one of the ideal tools for clinical decision-making that can be used to identify hemoglobin A1C (HbA

methods340TB smear positive patients attending two peri-urban clinics were recruited and prospectively followed up for six months. Baseline HbA

resultsOf the 340 patients enrolled: 84%were cured, 7% completed therapy and 9% had unfavorable outcomes out of which 4% (n = 32) had microbiologic failure. Using CART HbA

conclusionUsing fractal geometry relationships to drug pharmacokinetics, low weight has profound influence on failure of anti-tuberculosis treatment among patients at risk for diabetes mellitus.

Indexed as

Fractal geometryHollow fiberHyperglycemiaTuberculosis outcomes

Identifiers

PMID31720385
PMCPMC6830151

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.