Evidence map›Paper›PMID 31720380›Full record

ArticleJournal of clinical tuberculosis and other mycobacterial diseases2018

A patient with central nervous system tuberculomas and a history of disseminated multi-drug-resistant tuberculosis.

Samantha R Kaplan, Jeffrey Topal, Lynn Sosa, Maricar Malinis, Anita Huttner, Ajay Malhotra, Gerald Friedland

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Journal of clinical tuberculosis and other mycobacterial diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Drug-resistant strains ofFrontiers in cellular and infection microbiology · 2023
    Review
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Samantha R KaplanYale School of Medicine, Department of Internal Medicine, Section of Infectious Diseases, AIDS Program, 135 College St, New Haven, CT 06510, United States.
Jeffrey TopalYale School of Medicine, Department of Internal Medicine, Section of Infectious Diseases, AIDS Program, 135 College St, New Haven, CT 06510, United States.
Lynn SosaConnecticut Department of Public Health, 410 Capitol Avenue, Hartford, CT 06134, United States.
Maricar MalinisYale School of Medicine, Department of Internal Medicine, Section of Infectious Diseases, AIDS Program, 135 College St, New Haven, CT 06510, United States.
Anita HuttnerYale School of Medicine, Department of Pathology, 333 Cedar St, New Haven, CT 06510, United States.
Ajay MalhotraYale School of Medicine, Department of Radiology, 333 Cedar St, New Haven, CT 06510, United States.
Gerald FriedlandYale School of Medicine, Department of Internal Medicine, Section of Infectious Diseases, AIDS Program, 135 College St, New Haven, CT 06510, United States.
Yale University · USConnecticut Department of Public Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tuberculosis (TB) is one of the leading causes of death worldwide, particularly in low- and middle-income countries. The global rates and numbers of drug resistant TB are rising. With increasing globalization, the spread of drug-resistant strains of TB has become a mounting global public health concern. We present a case of a young man previously treated for multi-drug resistant (MDR) TB in India who presented with neurological symptoms and central nervous system TB in the United States. His case highlights unique diagnostic and treatment challenges that are likely to become more commonplace with the increase of patients infected with drug-resistant TB and complicated extrapulmonary disease.

Indexed as

AFB, acid-fast bacilliBAL, bronchoalveolar lavageBedaquilineCentral nervous system (CNS) TBCNS, central nervous systemCSF, cerebrospinal fluidCT, computerized tomographyDOT, directly observed therapyDST, drug susceptibility testingExtensively drug-resistant tuberculosis (XDR-TB)FDA, Food and Drug AdministrationIV, intravenousLUL, left upper lobeMDR-TB, multidrug-resistant tuberculosisMRI, magnetic resonance imagingMulti-drug resistant tuberculosis (MDR-TB)TB, tuberculosisTuberculomaTuberculosis (TB)WHO, World Health OrganizationXDR-TB, extensively drug-resistant tuberculosis

Identifiers

PMID31720380
PMCPMC6830180
OpenAlexW2775762225

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.