Evidence map›Paper›PMID 31720314›Full record

ArticleJournal of medical imaging (Bellingham, Wash.)2019

SLICR super-voxel algorithm for fast, robust quantification of myocardial blood flow by dynamic computed tomography myocardial perfusion imaging.

Hao Wu, Brendan L Eck, Jacob Levi, Anas Fares, Yuemeng Li, Di Wen, Hiram G Bezerra, Raymond F Muzic, David L Wilson

Abstract read
In one paragraph

Article in Journal of medical imaging (Bellingham, Wash.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hao WuCase Western Reserve University, Department of Biomedical Engineering, Cleveland, Ohio, United States.
Brendan L EckCase Western Reserve University, Department of Biomedical Engineering, Cleveland, Ohio, United States.ORCID https://orcid.org/0000-0003-0971-4432
Jacob LeviCase Western Reserve University, Department of Physics, Cleveland, Ohio, United States.
Anas FaresUniversity Hospitals Cleveland Medical Center, Harrington Heart and Vascular Institute, Cardiovascular Imaging Core Laboratory, Cleveland, Ohio, United States.
Yuemeng LiCase Western Reserve University, Department of Biomedical Engineering, Cleveland, Ohio, United States.ORCID https://orcid.org/0000-0002-8796-1503
Di WenCase Western Reserve University, Department of Biomedical Engineering, Cleveland, Ohio, United States.
Hiram G BezerraUniversity Hospitals Cleveland Medical Center, Harrington Heart and Vascular Institute, Cardiovascular Imaging Core Laboratory, Cleveland, Ohio, United States.
Raymond F MuzicCase Western Reserve University, Department of Biomedical Engineering, Cleveland, Ohio, United States.ORCID https://orcid.org/0000-0001-9986-4674
David L WilsonCase Western Reserve University, Department of Biomedical Engineering, Cleveland, Ohio, United States.

Funding

Interdisciplinary Biomedical Imaging Training ProgramT32EB007509 · NIBIB · CASE WESTERN RESERVE UNIVERSITY · PI DAVID Lynn WILSON, Xin Yu · 2007 to 2026
$5.6M
System-independent quantitative cardiac CT perfusionR44HL156811 · NHLBI · BIOINVISION, INC. · PI ROY, DEBASHISH, WILSON, DAVID LYNN · 2021 to 2022
$2.0M
System-independent quantitative cardiac CT perfusionR41HL144271 · NHLBI · BIOINVISION, INC. · PI WILSON, DAVID LYNN · 2018 to 2018
$224k
BIOMEDICAL ENGINEERING RESEARCH FACILITIESC06RR012463 · NCRR · CASE WESTERN RESERVE UNIVERSITY · PI KUTINA, KENNETH L · 1997 to 1997
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NCRR NIH HHS C06 RR012463NHLBI NIH HHS R41 HL144271NHLBI NIH HHS R44 HL156811NIBIB NIH HHS T32 EB007509
6 · The paper itself

Abstract

We created and evaluated a processing method for dynamic computed tomography myocardial perfusion imaging (CT-MPI) of myocardial blood flow (MBF), which combines a modified simple linear iterative clustering algorithm (SLIC) with robust perfusion quantification, hence the name SLICR. SLICR adaptively segments the myocardium into nonuniform super-voxels with similar perfusion time attenuation curves (TACs). Within each super-voxel, an α-trimmed-median TAC was computed to robustly represent the super-voxel and a robust physiological model (RPM) was implemented to semi-analytically estimate MBF. SLICR processing was compared with another voxel-wise MBF preprocessing approach, which included a spatiotemporal bilateral filter (STBF) for noise reduction prior to perfusion quantification. Image data from a digital CT-MPI phantom and a porcine ischemia model were evaluated. SLICR was

Indexed as

blood flow quantificationcardiac perfusion imagingclusteringcomputed tomographyimage processingparameter estimation

Identifiers

PMID31720314
PMCPMC6833456

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.