ArticleERJ open research2019
Time to diagnosis of tuberculosis is greater in older patients: a retrospective cohort review.
Article in ERJ open research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.
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Who cites it
31 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Long-term health effects of antipyretic drug use in the aging population: a systematic review.Journal of medicine and life · 2024Pooled it
- Duration and determinants of delayed tuberculosis diagnosis and treatment in high-burden countries: a mixed-methods systematic review and meta-analysis.Respiratory research · 2021Pooled it
- Tuberculosis Development in Chronic Obstructive Pulmonary Disease: A Nationwide Population-Based Study.Journal of Korean medical science · 2026Article
- Rural Residence and One-Person Households Are Associated with Diagnostic Delay in Pulmonary Tuberculosis in a Low-Incidence European Setting.Tropical medicine and infectious disease · 2026Article
- Prediction of Tuberculosis Risk in the Elderly Population of Eastern China: Development and Validation of Multiple Machine Learning Models.Infection and drug resistance · 2026Article
- The impact of population aging on tuberculosis prevention and control in Shanghai: a prediction based on age-period-cohort models.Aging clinical and experimental research · 2025Article
- Tuberculosis Incidence and Outcomes Among Older New Yorkers.Open forum infectious diseases · 2025Article
- Diagnostic delays of periodontitis and associated factors: a cross-sectional study.Clinical oral investigations · 2024Article
- Global, regional, and national age-specific progress towards the 2020 milestones of the WHO End TB Strategy: a systematic analysis for the Global Burden of Disease Study 2021.The Lancet. Infectious diseases · 2024Article
- High all-cause mortality and increasing proportion of older adults with tuberculosis in Texas, 2008-2020.Epidemiology and infection · 2024Article
- Article
- Timely Pulmonary Tuberculosis Diagnosis Based on the Epidemiological Disease Spectrum: Population-Based Prospective Cohort Study in the Republic of Korea.JMIR public health and surveillance · 2024Article
- Analysis of factors influencing bronchiectasis patients with active pulmonary tuberculosis and development of a nomogram prediction model.Frontiers in medicine · 2024Article
- The epidemiological situation of tuberculosis in Spain according to surveillance and hospitalization data, 2012-2020.PloS one · 2024Article
- Article
- Assessment of Effective Anti-TB Regimens and Adverse Outcomes Related Risk Factors in the Elderly and Senile-Aged TB Patients.Infection and drug resistance · 2023Article
- Tuberculosis Disease Among Adults Aged 65 Years and Older: Alameda County, California, 2016-2019.Open forum infectious diseases · 2022Article
- Tuberculosis in an Aging World.Pathogens (Basel, Switzerland) · 2022Review
- A narrative review of tuberculosis in the United States among persons aged 65 years and older.Journal of clinical tuberculosis and other mycobacterial diseases · 2022Review
- Intestinal perforation due to miliary tuberculosis in a patient with myasthenia gravis.BMJ case reports · 2022Article
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionAge-related immunosenescence influences the presentation of tuberculosis (TB) in older patients. Here, we explore the clinical and radiological presentation of TB in the elderly and the factors associated with time to treatment for TB.
methodsThis is a retrospective cohort study comparing the clinical, radiological and demographic characteristics of TB patients aged ≥65 years with TB patients aged 18-64 years in a large cohort of TB patients in the UK. Factors associated with the time to presentation and time to treatment were identified using a multivariable analysis model.
results1023 patients were included in the analyses: 679 patients aged 18-64 years and 344 patients aged ≥65 years. "Classical" symptoms of TB (cough, haemoptysis, fever, nights sweats and weight loss) were less common among older patients with pulmonary TB (PTB) (p<0.05), but dyspnoea was more common among older patients (p=0.001). Time from presenting in secondary care to starting treatment was shorter in younger compared with older patients: 3
conclusionsOlder patients aged ≥65 years with TB had fewer "classical" clinical and radiological presentations of TB, which may explain longer times to starting treatment from symptom onset compared with younger patients aged <65 years.
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