Evidence map›Paper›PMID 31719574›Full record

ArticleScientific reports2019

Alteration of the lysophosphatidic acid and its precursor lysophosphatidylcholine levels in spinal cord stenosis: A study using a rat cauda equina compression model.

Baasanjav Uranbileg, Nobuko Ito, Makoto Kurano, Daisuke Saigusa, Ritsumi Saito, Akira Uruno, Kuniyuki Kano, Hitoshi Ikeda, Yoshitsugu Yamada, Masahiko Sumitani and 3 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Metabolism of sphingolipids in a rat spinal cord stenosis model.Biochemistry and biophysics reports · 2025
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Lysophosphatidylcholine: Potential Target for the Treatment of Chronic Pain.International journal of molecular sciences · 2022
    Review
  13. Lysophospholipid Mediators in Health and Disease.Annual review of pathology · 2022
    Review
  14. Review
  15. Article
  16. Review
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Baasanjav UranbilegDepartment of Clinical Laboratory Medicine, The University of Tokyo, Tokyo, Japan.
Nobuko ItoDepartment of Anesthesiology and Pain Relief Center, The University of Tokyo, Tokyo, Japan. nobuko-tky@umin.ac.jp.ORCID http://orcid.org/0000-0001-9581-3925
Makoto KuranoDepartment of Clinical Laboratory Medicine, The University of Tokyo, Tokyo, Japan.
Daisuke SaigusaDepartment of Integrative Genomics, Tohoku Medical Megabank Organization, Miyagi, Japan.
Ritsumi SaitoDepartment of Integrative Genomics, Tohoku Medical Megabank Organization, Miyagi, Japan.
Akira UrunoDepartment of Integrative Genomics, Tohoku Medical Megabank Organization, Miyagi, Japan.
Kuniyuki KanoLaboratory of Molecular and Cellular Biochemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, Miyagi, Japan.
Hitoshi IkedaDepartment of Clinical Laboratory Medicine, The University of Tokyo, Tokyo, Japan.
Yoshitsugu YamadaDepartment of Anesthesiology and Pain Relief Center, The University of Tokyo, Tokyo, Japan.
Masahiko SumitaniDepartment of Pain and Palliative Medicine, The University of Tokyo Hospital, Tokyo, Japan.
Miho SekiguchiDepartment of Orthopaedic Surgery, Fukushima Medical University, School of Medicine, Fukushima, Japan.
Junken AokiLaboratory of Molecular and Cellular Biochemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, Miyagi, Japan.ORCID http://orcid.org/0000-0001-9435-1896
Yutaka YatomiDepartment of Clinical Laboratory Medicine, The University of Tokyo, Tokyo, Japan.
The University of Tokyo · JPTohoku University · JPFukushima Medical University · JPUniversity of Tokyo Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cauda equina compression (CEC) is a major cause of neurogenic claudication and progresses to neuropathic pain (NP). A lipid mediator, lysophosphatidic acid (LPA), is known to induce NP via the LPA

Indexed as

AnimalsCauda EquinaConstriction, PathologicDisease Models, AnimalFemaleGene Expression RegulationLysophosphatidylcholinesLysophospholipidsNeuralgiaRats, Sprague-DawleyReceptors, Lysophosphatidic AcidRNA, MessengerSpinal Cordlysophosphatidic acidLysophosphatidylcholinesLysophospholipidsReceptors, Lysophosphatidic AcidRNA, Messenger

Identifiers

PMID31719574
PMCPMC6851136
OpenAlexW2987172592

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.