Evidence map›Paper›PMID 31719543›Full record

ArticleScientific reports2019

High-frequency oscillations in scalp EEG mirror seizure frequency in pediatric focal epilepsy.

Ece Boran, Johannes Sarnthein, Niklaus Krayenbühl, Georgia Ramantani, Tommaso Fedele

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 60 citations in OpenAlex.

  1. Article
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  4. Mapping epileptogenic brain using a unified spatial-temporal-spectral source imaging framework.Proceedings of the National Academy of Sciences of the United States of America · 2025
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  12. EEG biomarker candidates for the identification of epilepsy.Clinical neurophysiology practice · 2023
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Ece BoranKlinik für Neurochirurgie, UniversitätsSpital & Universität Zürich, Zürich, Switzerland.ORCID http://orcid.org/0000-0002-0395-7575
Johannes SarntheinKlinik für Neurochirurgie, UniversitätsSpital & Universität Zürich, Zürich, Switzerland.ORCID http://orcid.org/0000-0001-9141-381X
Niklaus KrayenbühlKlinik für Neurochirurgie, UniversitätsSpital & Universität Zürich, Zürich, Switzerland.
Georgia RamantaniNeuropädiatrie, Universitäts-Kinderspital Zürich, Zürich, Switzerland.
Tommaso FedeleInstitute of Cognitive Neuroscience, Higher School of Economics - National Research University, Moscow, Russian Federation. tofedele@hse.ru.
University of Zurich · CHNational Research University Higher School of Economics · RUUniversity Children's Hospital Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High-frequency oscillations (HFO) are promising EEG biomarkers of epileptogenicity. While the evidence supporting their significance derives mainly from invasive recordings, recent studies have extended these observations to HFO recorded in the widely accessible scalp EEG. Here, we investigated whether scalp HFO in drug-resistant focal epilepsy correspond to epilepsy severity and how they are affected by surgical therapy. In eleven children with drug-resistant focal epilepsy that underwent epilepsy surgery, we prospectively recorded pre- and postsurgical scalp EEG with a custom-made low-noise amplifier (LNA). In four of these children, we also recorded intraoperative electrocorticography (ECoG). To detect clinically relevant HFO, we applied a previously validated automated detector. Scalp HFO rates showed a significant positive correlation with seizure frequency (R

Indexed as

ElectroencephalographyAdolescentAmplifiers, ElectronicChildChild, PreschoolElectrocorticographyEpilepsies, PartialFemaleHumansInfantMaleReproducibility of ResultsScalpSeizures

Identifiers

PMID31719543
PMCPMC6851354
OpenAlexW2989331666

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.